4-Ethoxysalicylic acid

Base Information

Chemical Name:4-Ethoxysalicylic acid
CAS No.:10435-55-9
Molecular Formula:C9H10 O4
Molecular Weight:182.176
Hs Code.:2918990090
European Community (EC) Number:233-919-2
NSC Number:4145
UNII:6V63RAH3E9
DSSTox Substance ID:DTXSID30146400
Nikkaji Number:J212.394K
Wikidata:Q83011206
ChEMBL ID:CHEMBL3134412
Mol file:10435-55-9.mol

Synonyms:4-Ethoxy-2-hydroxybenzoic acid;4-Ethoxysalicylic acid;10435-55-9;Benzoic acid, 4-ethoxy-2-hydroxy-;AI3-24368;2-hydroxy-4-ethoxybenzoic acid;CHEMBL3134412;NSC-4145;EINECS 233-919-2;Salicylic acid, 4-ethoxy-;SCHEMBL539138;4-Ethoxysalicylic acid, 97%;6V63RAH3E9;4-ethoxy-2-hydroxy-benzoic acid;DTXSID30146400;NSC4145;NSC 4145;BDBM50496619;AKOS015889273;WS-02277;CS-0440208;FT-0731860;D85914;J-001156

Suppliers and Price of 4-Ethoxysalicylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Ethoxysalicylic acid
50mg
$ 60.00

TRC
4-Ethoxysalicylic acid
25mg
$ 45.00

Sigma-Aldrich
4-Ethoxysalicylic acid 97%
5g
$ 115.00

Sigma-Aldrich
4-ETHOXY-2-HYDROXYBENZOIC ACID AldrichCPR
1g
$ 33.40

Sigma-Aldrich
4-Ethoxysalicylic acid 97%
1g
$ 32.30

Crysdot
4-ETHOXY-2-HYDROXYBENZOIC ACID 95+%
100g
$ 679.00

American Custom Chemicals Corporation
4-ETHOXYSALICYLIC ACID 95.00%
1G
$ 640.33

American Custom Chemicals Corporation
4-ETHOXYSALICYLIC ACID 95.00%
5G
$ 911.38

Alichem
4-ETHOXY-2-HYDROXYBENZOIC ACID
10g
$ 696.07

Alichem
4-ETHOXY-2-HYDROXYBENZOIC ACID
5g
$ 468.10

Total 15 raw suppliers

Chemical Property of 4-Ethoxysalicylic acid

Chemical Property:

Vapor Pressure:4.04E-05mmHg at 25°C
Melting Point:153-157 °C(lit.)
Boiling Point:337.7°Cat760mmHg
Flash Point:137.5°C
PSA：66.76000
Density:1.292g/cm³
LogP:1.48910
XLogP3:2.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:182.05790880
Heavy Atom Count:13
Complexity:181

Purity/Quality:

99% ^*data from raw suppliers

4-Ethoxysalicylic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CCOC1=CC(=C(C=C1)C(=O)O)O

Technology Process of 4-Ethoxysalicylic acid

There total 15 articles about 4-Ethoxysalicylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 74-96-4
ethyl bromide

: 89-86-1
4-hydroxysalicylic acid

: 10435-55-9
4-ethoxy-2-hydroxybenzoic acid

Guidance literature:: With alkali hydroxide; In ethanol; water; at 60 ℃; for 16h;
DOI:10.1002/chem.201702742

Reference yield:

: 7-ethoxy-2-(2-ethoxy-phenyl)-chromen-4-one

: 141-52-6
sodium ethanolate

: 37470-42-1
1-(4-ethoxy-2-hydroxyphenyl)ethanone

: 10435-55-9
4-ethoxy-2-hydroxybenzoic acid

: 134-11-2
2-ethoxybenzoic acid

Guidance literature:

Reference yield:

: 621-34-1
O-ethyl resorcinol

: 298-14-6
potassium hydrogencarbonate

: 10435-55-9
4-ethoxy-2-hydroxybenzoic acid

Guidance literature:: With 2,3-dihydroxybenzoate decarboxylase from Aspergillus oryzae; In aq. phosphate buffer; at 30 ℃; for 24h; regioselective reaction; Enzymatic reaction;
DOI:10.1039/c3ra47719c