N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine

Base Information Edit

Chemical Name:N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine
CAS No.:179552-74-0
Molecular Formula:C15 H10 Cl F N4 O3
Molecular Weight:348.721
Hs Code.:
Mol file:179552-74-0.mol

Synonyms:(3-chloro-4-fluoro-phenyl)-(7-methoxy-6-nitro-quinazolin-4-yl)-amine;3-Chloro4-fluoro-phenyl-(7-methoxy-6-nitro-quinazoline-4-yl)-amine;4-(3-chloro-4-fluoroanilino)-7-methoxy-6-nitroquinazoline;4-(3-chloro-4-fluorophenylamino)-6-nitro-7-methoxyquinazoline;

Suppliers and Price of N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine
1g
$ 160.00

TRC
N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine
10g
$ 1260.00

Crysdot
N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine 97%
25g
$ 574.00

Crysdot
N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine 97%
10g
$ 287.00

Chemenu
N-(3-chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine 97%
10g
$ 271.00

Chemenu
N-(3-chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine 97%
5g
$ 184.00

Chemenu
N-(3-chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine 97%
25g
$ 542.00

Ambeed
N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine 97%
25g
$ 552.00

Ambeed
N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine 97%
10g
$ 307.00

Ambeed
N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine 97%
1g
$ 103.00

Total 60 raw suppliers

Chemical Property of N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine Edit

Chemical Property:

Boiling Point:515.5±50.0 °C(Predicted)
PKA:5.07±0.70(Predicted)
PSA：92.86000
Density:1.529±0.06 g/cm3(Predicted)
LogP:4.67890
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

99% ^*data from raw suppliers

N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine is a useful synthetic intermediate in the synthesis of Afatinib (A355300); an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.

Technology Process of N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine

There total 16 articles about N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%