6-METHYL-3,4-DIHYDRO-2H-PYRIDO[3,2-B][1,4]OXAZINE

Base Information

• Chemical Name: 6-METHYL-3,4-DIHYDRO-2H-PYRIDO[3,2-B][1,4]OXAZINE
• CAS No.: 20567-67-3
• Molecular Formula: C₈H₁₀N₂O
• Molecular Weight: 150.18
• Hs Code.: 2934999090
• Mol file: 20567-67-3.mol

Synonyms:6-METHYL-3,4-DIHYDRO-2H-PYRIDO[3,2-B][1,4]OXAZINE;2H-Pyrido[3,2-b]-1,4-oxazine, 3,4-dihydro-6-methyl-

Chemical Property of 6-METHYL-3,4-DIHYDRO-2H-PYRIDO[3,2-B][1,4]OXAZINE

Chemical Property:

• PSA: 34.15000
• LogP: 1.33230

Purity/Quality:

97% ^*data from raw suppliers

6-Methyl-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-METHYL-3,4-DIHYDRO-2H-PYRIDO[3,2-B][1,4]OXAZINE

There total 4 articles about 6-METHYL-3,4-DIHYDRO-2H-PYRIDO[3,2-B][1,4]OXAZINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

6-methyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4h)-one (20348-10-1) → 6-methyl-3,4-dihydro-2h-pyrido[3,2-b][1,4]oxazine (20567-67-3)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 3h;

DOI:10.1016/j.bmcl.2005.01.028

Reference yield:

6-methyl-2-nitropyridin-3-ol (15128-90-2) → 6-methyl-3,4-dihydro-2h-pyrido[3,2-b][1,4]oxazine (20567-67-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 99 percent / H₂ / Pd/C / ethyl acetate

2: 79 percent / aq. NaHCO₃ / butan-2-one

3: 99 percent / lithium aluminum hydride / tetrahydrofuran / 3 h / 20 °C

With lithium aluminium tetrahydride; hydrogen; sodium hydrogencarbonate; palladium on activated charcoal; In tetrahydrofuran; ethyl acetate; butanone;

DOI:10.1016/j.bmcl.2005.01.028

Reference yield:

2-amino-3-hydroxy-6-methylpyridine (20348-16-7) → 6-methyl-3,4-dihydro-2h-pyrido[3,2-b][1,4]oxazine (20567-67-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 79 percent / aq. NaHCO₃ / butan-2-one

2: 99 percent / lithium aluminum hydride / tetrahydrofuran / 3 h / 20 °C

With lithium aluminium tetrahydride; sodium hydrogencarbonate; In tetrahydrofuran; butanone;

DOI:10.1016/j.bmcl.2005.01.028

upstream raw materials:

6-methyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4h)-one

2-amino-3-hydroxy-6-methylpyridine

6-methyl-2-nitropyridin-3-ol

Downstream raw materials:

2,3-dihydro-6-methyl-4H-pyrido[3,2-b]-1,4-oxazine-4-carboxylic acid, 1,1-dimethylethyl ester

6-[2-(3-methyl-4-nitro-phenoxy)-ethyl]-2,3-dihydro-pyrido[3,2-b][1,4]oxazine-4-carboxylic acid tert-butyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 20567-67-3 6-METHYL-3,4-DIHYDRO-2H-PYRIDO[3,2-B][1,4]OXAZINE

Send

Send

Metric Ton KG G Pound L ML

Send

Send