6-METHYL-4H-PYRIDO[3,2-B][1,4]OXAZIN-3-ONE

Base Information

Chemical Name:6-METHYL-4H-PYRIDO[3,2-B][1,4]OXAZIN-3-ONE
CAS No.:20348-10-1
Molecular Formula:C₈H₈N₂O₂
Molecular Weight:164.164
Hs Code.:2934999090
Mol file:20348-10-1.mol

Synonyms:6-METHYL-4H-PYRIDO[3,2-B][1,4]OXAZIN-3-ONE;2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one, 6-methyl-

Suppliers and Price of 6-METHYL-4H-PYRIDO[3,2-B][1,4]OXAZIN-3-ONE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Methyl-4H-pyrido[3,2-b][1,4]oxazin-3-one
100mg
$ 175.00

TRC
6-Methyl-4H-pyrido[3,2-b][1,4]oxazin-3-one
50mg
$ 110.00

Matrix Scientific
6-Methyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
1g
$ 540.00

Matrix Scientific
6-Methyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
5g
$ 1296.00

Matrix Scientific
6-Methyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
10g
$ 1872.00

J&W Pharmlab
6-Methyl-4H-pyrido[3,2-b][1,4]oxazin-3-one 97%
5g
$ 1400.00

J&W Pharmlab
6-Methyl-4H-pyrido[3,2-b][1,4]oxazin-3-one 97%
1g
$ 350.00

J&W Pharmlab
6-Methyl-4H-pyrido[3,2-b][1,4]oxazin-3-one 97%
500mg
$ 225.00

Crysdot
6-Methyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one 95+%
1g
$ 581.00

Chemcia Scientific
6-Methyl-4H-pyrido[3,2-b][1,4]oxazin-3-one 95%
1 G
$ 450.00

Total 10 raw suppliers

Chemical Property of 6-METHYL-4H-PYRIDO[3,2-B][1,4]OXAZIN-3-ONE

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:363.073°C at 760 mmHg
Flash Point:173.381°C
PSA：54.71000
Density:1.269g/cm³
LogP:0.80600

Purity/Quality:

97% ^*data from raw suppliers

6-Methyl-4H-pyrido[3,2-b][1,4]oxazin-3-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6-METHYL-4H-PYRIDO[3,2-B][1,4]OXAZIN-3-ONE

There total 4 articles about 6-METHYL-4H-PYRIDO[3,2-B][1,4]OXAZIN-3-ONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 20348-16-7
2-amino-3-hydroxy-6-methylpyridine

: 79-04-9
chloroacetyl chloride

: 20348-10-1
6-methyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4h)-one

Guidance literature:: With sodium hydrogencarbonate; In butanone;
DOI:10.1016/j.bmcl.2005.01.028

Reference yield: 62.0%

: 20348-16-7
2-amino-3-hydroxy-6-methylpyridine

: 96-34-4
methyl chloroacetate

: 20348-10-1
6-methyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4h)-one

Guidance literature:: 2-amino-3-hydroxy-6-methylpyridine; With sodium hydride; In dimethyl sulfoxide; for 0.25h;

methyl chloroacetate; In dimethyl sulfoxide; at 100 ℃; for 3.5h;

Reference yield:

: 15128-90-2
6-methyl-2-nitropyridin-3-ol

: 20348-10-1
6-methyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4h)-one

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / H₂ / Pd/C / ethyl acetate

2: 79 percent / aq. NaHCO₃ / butan-2-one

With hydrogen; sodium hydrogencarbonate; palladium on activated charcoal; In ethyl acetate; butanone;
DOI:10.1016/j.bmcl.2005.01.028