3-Amino-2'-methylbiphenyl

Base Information

• Chemical Name: 3-Amino-2'-methylbiphenyl
• CAS No.: 400745-54-2
• Molecular Formula: C13H13N
• Molecular Weight: 183.253
• Hs Code.: 2921499090
• European Community (EC) Number: 673-288-4
• Nikkaji Number: J2.485.265B
• Mol file: 400745-54-2.mol

Synonyms:400745-54-2;3-amino-2'-methylbiphenyl;2'-Methyl-[1,1'-biphenyl]-3-amine;3-(2-methylphenyl)aniline;2'-methylbiphenyl-3-ylamine;2'-methylbiphenyl-3-amine;[1,1'-Biphenyl]-3-amine, 2'-methyl-;2'-Methyl-biphenyl-3-ylamine;(2'-methylbiphenyl-3-yl)amine;MFCD03424663;2'-methyl[1,1'-biphenyl]-3-amine;m-tolylphenylamine;m-Toluylphenylamin;2'-methyl [1,1'-biphenyl]-3-amine;3-(2'-Tolyl)aniline;2'-Methyl-3-biphenylamine;2'-Methyl-biphenyl-3-amine;SCHEMBL1037202;AC1625;STK701239;AKOS002683466;AB92594;CS-11907;SY032942;BB 0222456;CS-0206478;FT-0704977;EN300-1142107;A873483;3-Amino-2 inverted exclamation mark -methylbiphenyl

Chemical Property of 3-Amino-2'-methylbiphenyl

Chemical Property:

• Boiling Point: 334.1oC at 760 mmHg
• Flash Point: 167.7oC
• PSA: 26.02000
• Density: 1.057g/cm3
• LogP: 3.82540
• Storage Temp.: 2-8°C(protect from light)
• XLogP3: 3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 183.104799419
• Heavy Atom Count: 14
• Complexity: 178

Purity/Quality:

97% ^*data from raw suppliers

2''-Methyl-[1,1''-biphenyl]-3-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC=CC=C1C2=CC(=CC=C2)N

Technology Process of 3-Amino-2'-methylbiphenyl

There total 12 articles about 3-Amino-2'-methylbiphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

m-nitrobromobenzene (585-79-5) + 2-Methylphenylboronic acid (16419-60-6) → 3‐(2‐methylphenyl)aniline (400745-54-2)

Guidance literature:

With β-D-mannose; palladium diacetate; potassium carbonate; In water; N,N-dimethyl-formamide; at 130 ℃; for 1h; Microwave irradiation; Green chemistry;

DOI:10.1039/c5ra04129e

Reference yield: 92.0%

o-tolyltris(2-propoxy)titanium (676270-02-3) + m-Bromoaniline (591-19-5) → 3‐(2‐methylphenyl)aniline (400745-54-2)

Guidance literature:

o-tolyltris(2-propoxy)titanium; With N-(diphenylphosphino)-2-phenyl-1H-indole; palladium diacetate; In toluene; for 0.0833333h; Inert atmosphere;

m-Bromoaniline; In toluene; at 90 ℃; for 1h; Inert atmosphere;

DOI:10.1002/anie.200904033

Reference yield: 91.0%

triethoxy(o-tolyl)silane (18412-55-0) + 3-chloro-aniline (108-42-9) → 3‐(2‐methylphenyl)aniline (400745-54-2)

Guidance literature:

With Pd((CH₃)2C₆H₃NC(CH₃)CHC(CH₃)NC₆H₃(CH₃)2)(CH₃)(P(CH₂CH₃)3); tetrabutylammomium bromide; sodium hydroxide; In water; at 60 ℃; for 10h; Inert atmosphere;

DOI:10.1039/c0cc03535a

upstream raw materials:

3-nitro-2'-methylbiphenyl

2-Methylphenylboronic acid

3-chloro-aniline

1-(3-nitrophenyl)-3,3-dimethyltriazene

Downstream raw materials:

(3-benzyl-3H-imidazol-4-ylmethyl)-(2'-methyl-biphenyl-3-yl)-amine