1-(4-Bromo-3-fluorophenyl)-2-chloroethanone

Base Information

Chemical Name:1-(4-Bromo-3-fluorophenyl)-2-chloroethanone
CAS No.:1260857-14-4
Molecular Formula:C8H5BrClFO
Molecular Weight:251.483
Hs Code.:
DSSTox Substance ID:DTXSID60693598
Wikidata:Q72456400
Mol file:1260857-14-4.mol

Synonyms:1-(4-Bromo-3-fluorophenyl)-2-chloroethanone;1260857-14-4;1-(4-Bromo-3-fluorophenyl)-2-chloroethan-1-one;1-(4-Bromo-3-fluorophenyl)-2-chloroethanone, 99per cent;SCHEMBL2686773;DTXSID60693598;KWURIFGJSWLEKB-UHFFFAOYSA-N;AMY25997;MFCD11847747;AKOS015853340;AS-41324;CS-0268732;1-(4-bromo-3-fluoro-phenyl)-2-chloro-ethanone;2-chloro-1-(4-bromo-3-fluoro-phenyl)-ethanone;EN300-1911202;A850226;Ethanone, 1-(4-bromo-3-fluorophenyl)-2-chloro-;1-(4-Bromo-3-fluorophenyl)-2-chloroethanone, 99%

Suppliers and Price of 1-(4-Bromo-3-fluorophenyl)-2-chloroethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
1-(4-Bromo-3-fluorophenyl)-2-chloroethanone 95+%
1g
$ 1143.00

Matrix Scientific
1-(4-Bromo-3-fluorophenyl)-2-chloroethanone 95+%
250mg
$ 515.00

Crysdot
1-(4-Bromo-3-fluorophenyl)-2-chloroethanone 97%
5g
$ 1190.00

Crysdot
1-(4-Bromo-3-fluorophenyl)-2-chloroethanone 97%
1g
$ 397.00

American Custom Chemicals Corporation
1-(4-BROMO-3-FLUOROPHENYL)-2-CHLOROETHANONE 95.00%
5MG
$ 499.75

Alichem
1-(4-Bromo-3-fluorophenyl)-2-chloroethanone
1g
$ 404.94

Alichem
1-(4-Bromo-3-fluorophenyl)-2-chloroethanone
5g
$ 1213.80

AK Scientific
1-(4-Bromo-3-fluorophenyl)-2-chloroethanone
1g
$ 1593.00

Total 12 raw suppliers

Chemical Property of 1-(4-Bromo-3-fluorophenyl)-2-chloroethanone

Chemical Property:

Boiling Point:309.8±32.0 °C(Predicted)
PSA：17.07000
Density:1.646
LogP:3.00970
Storage Temp.:2-8°C
XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:249.91963
Heavy Atom Count:12
Complexity:176

Purity/Quality:

97% ^*data from raw suppliers

1-(4-Bromo-3-fluorophenyl)-2-chloroethanone 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1C(=O)CCl)F)Br

Technology Process of 1-(4-Bromo-3-fluorophenyl)-2-chloroethanone

There total 3 articles about 1-(4-Bromo-3-fluorophenyl)-2-chloroethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 67442-07-3
2-chloro-N-methoxy-N-methylacetamide

: 136434-77-0
4-bromo-3-fluoroiodobenzene

: 1260857-14-4
2-chloro-1-(4-bromo-3-fluorophenyl)-ethanone

Guidance literature:: 4-bromo-3-fluoroiodobenzene; With isopropylmagnesium chloride; In toluene; at -40 ℃; for 2.5h; Inert atmosphere;

2-chloro-N-methoxy-N-methylacetamide; In toluene; at -78 - 25 ℃; for 4h; Inert atmosphere;
DOI:10.1021/acs.oprd.1c00313

Reference yield:

: 695188-21-7
4-bromo-3-fluorobenzoyl chloride

: 18107-18-1
diazomethyl-trimethyl-silane

: 1260857-14-4
2-chloro-1-(4-bromo-3-fluorophenyl)-ethanone

Guidance literature:: 4-bromo-3-fluorobenzoyl chloride; diazomethyl-trimethyl-silane; In tetrahydrofuran; diethyl ether; acetonitrile; at 0 - 20 ℃; for 0.5h;

With hydrogenchloride; In tetrahydrofuran; diethyl ether; water; acetonitrile; at 0 - 20 ℃; for 0.5h;

Reference yield:

: 695188-21-7
4-bromo-3-fluorobenzoyl chloride

: 18107-18-1
diazomethyl-trimethyl-silane

: 1003879-02-4
2-bromo-1-(4-bromo-3-fluorophenyl)ethanone

: 1260857-14-4
2-chloro-1-(4-bromo-3-fluorophenyl)-ethanone

Guidance literature:: 4-bromo-3-fluorobenzoyl chloride; diazomethyl-trimethyl-silane; In tetrahydrofuran; diethyl ether; acetonitrile; at 0 - 20 ℃; for 0.5h;

With hydrogen bromide; In tetrahydrofuran; diethyl ether; water; acetonitrile; at 0 - 20 ℃; for 1h;