1-(4-Fluoro-benzyl)-piperidine-4-carboxylic acid

Base Information

Chemical Name:1-(4-Fluoro-benzyl)-piperidine-4-carboxylic acid
CAS No.:193538-25-9
Molecular Formula:C13H16FNO2
Molecular Weight:273.73
Hs Code.:2933399090
DSSTox Substance ID:DTXSID70405144
Mol file:193538-25-9.mol

Synonyms:193538-25-9;1-(4-Fluoro-benzyl)-piperidine-4-carboxylic acid;1-(4-fluorobenzyl)piperidine-4-carboxylic acid;1-[(4-fluorophenyl)methyl]piperidine-4-carboxylic acid;4-Piperidinecarboxylic acid, 1-[(4-fluorophenyl)methyl]-;SCHEMBL6994717;DTXSID70405144;MFCD03371459;AKOS000125330;SB43424;BP-21494;BB 0220125;CS-0449442;FT-0744849;1-(4-fluorobenzyl)piperidine-4-carboxylicacid

Suppliers and Price of 1-(4-Fluoro-benzyl)-piperidine-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
1-(4-Fluorobenzyl)-piperidine-4-carboxylic acid
500 mg
$ 472.00

Matrix Scientific
1-(4-Fluoro-benzyl)-piperidine-4-carboxylic acid
1g
$ 308.00

Matrix Scientific
1-(4-Fluoro-benzyl)-piperidine-4-carboxylic acid
500mg
$ 188.00

Crysdot
1-(4-Fluorobenzyl)piperidine-4-carboxylicacid 95+%
5g
$ 795.00

Chemenu
1-(4-Fluorobenzyl)piperidine-4-carboxylicacid 95%
5g
$ 744.00

Apolloscientific
1-(4-Fluoro-benzyl)-piperidine-4-carboxylicacid
500mg
$ 295.00

American Custom Chemicals Corporation
1-(4-FLUORO-BENZYL)-PIPERIDINE-4-CARBOXYLIC ACID HYDROCHLORIDE 95.00%
500MG
$ 779.63

Alichem
1-(4-Fluorobenzyl)piperidine-4-carboxylicacid
5g
$ 858.60

Total 8 raw suppliers

Chemical Property of 1-(4-Fluoro-benzyl)-piperidine-4-carboxylic acid

Chemical Property:

Boiling Point:363.6±37.0 °C(Predicted)
PKA:4.02±0.20(Predicted)
PSA：40.54000
Density:1.234
LogP:2.06020
Storage Temp.:2-8°C
XLogP3:-0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:237.11650692
Heavy Atom Count:17
Complexity:256

Purity/Quality:

98%min ^*data from raw suppliers

1-(4-Fluorobenzyl)-piperidine-4-carboxylic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1C(=O)O)CC2=CC=C(C=C2)F

Technology Process of 1-(4-Fluoro-benzyl)-piperidine-4-carboxylic acid

There total 1 articles about 1-(4-Fluoro-benzyl)-piperidine-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 193538-24-8
1-[(4-Fluorophenyl)methyl]-4-(ethoxycarbonyl)-piperidine

: 193538-25-9
1-(4-Fluorobenzyl)piperidine-4-carboxylic acid

Guidance literature:: With hydrogenchloride; trifluoroacetic acid; for 2h; Heating;
DOI:10.1021/jm000311k

Reference yield: 50.0%

: C₁₇H₂₆N₄O₅

: 193538-25-9
1-(4-Fluorobenzyl)piperidine-4-carboxylic acid

: N-4-(4-fluorobenzylpiperidinyl)acyl-L-Asn-L-Val-NH-(2-hydroxy-4-methoxybenzyl)

Guidance literature:: With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In N,N-dimethyl-d₆-formamide; at 20 ℃;
DOI:10.1080/10286020.2021.1910241

Reference yield:

: 3963-62-0
2,2-Diphenylethylamine

: 193538-25-9
1-(4-Fluorobenzyl)piperidine-4-carboxylic acid

: 333364-06-0
4-[(2-diphenylethyl)aminocarbonyl]-1-[(4-fluorophenyl)methyl]piperidine

Guidance literature:: 1-(4-Fluorobenzyl)piperidine-4-carboxylic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 1h;

2,2-Diphenylethylamine; In dichloromethane; at 20 ℃; Further stages.;
DOI:10.1021/jm000311k