6-bromo-N-methylquinazolin-2-amine

Base Information

Chemical Name:6-bromo-N-methylquinazolin-2-amine
CAS No.:882670-77-1
Molecular Formula:C9H8BrN3
Molecular Weight:238.087
Hs Code.:
DSSTox Substance ID:DTXSID00582073
Wikidata:Q82473401
Mol file:882670-77-1.mol

Synonyms:6-bromo-N-methylquinazolin-2-amine;882670-77-1;6-BROMO-2-(N-METHYLAMINO)QUINAZOLINE;SCHEMBL1585490;DTXSID00582073;SVCYTTMHAGTBOR-UHFFFAOYSA-N;MFCD13191815;AKOS015834794;AS-61879;CS-0212540;EN300-307566;A842514;J-518449

Suppliers and Price of 6-bromo-N-methylquinazolin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
6-Bromo-N-methylquinazolin-2-amine 95+%
1g
$ 535.00

Chemenu
6-Bromo-N-methylquinazolin-2-amine 95%
1g
$ 505.00

American Custom Chemicals Corporation
6-BROMO-N-METHYLQUINAZOLIN-2-AMINE 95.00%
5MG
$ 496.78

Alichem
6-Bromo-N-methylquinazolin-2-amine
5g
$ 2121.70

Alichem
6-Bromo-N-methylquinazolin-2-amine
1g
$ 801.42

Alichem
6-Bromo-N-methylquinazolin-2-amine
250mg
$ 312.12

Total 13 raw suppliers

Chemical Property of 6-bromo-N-methylquinazolin-2-amine

Chemical Property:

Storage Temp.:Room temperature.
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:236.99016
Heavy Atom Count:13
Complexity:176

Purity/Quality:

97% ^*data from raw suppliers

6-Bromo-N-methylquinazolin-2-amine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNC1=NC=C2C=C(C=CC2=N1)Br

Technology Process of 6-bromo-N-methylquinazolin-2-amine

There total 3 articles about 6-bromo-N-methylquinazolin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 74-89-5
methylamine

: 190273-89-3
6-bromoquinazolin-2-ylamine

: 882670-77-1
(6-bromo-quinazolin-2-yl)-methylamine

Guidance literature:: With toluene-4-sulfonic acid; at 150 ℃; for 24h; under 42406.1 Torr;
DOI:10.1021/jm0605482

Reference yield:

: 882672-05-1
6-bromo-2-chloroquinazoline

: 74-89-5
methylamine

: 882670-77-1
(6-bromo-quinazolin-2-yl)-methylamine

Guidance literature:: In tetrahydrofuran; at 80 ℃; Autoclave;

Reference yield:

: 93777-26-5
5-bromo-2-fluorobenzaldehyde

: 882670-77-1
(6-bromo-quinazolin-2-yl)-methylamine

Guidance literature:: Multi-step reaction with 2 steps

1.1: NEt(i-Pr)2 / 1-methyl-pyrrolidin-2-one / 150 - 160 °C

1.2: 48 percent / 1-methyl-pyrrolidin-2-one / 150 - 160 °C

2.1: 68 percent / p-toluenesulfonic acid monohydrate / 24 h / 150 °C / 42406.1 Torr

With toluene-4-sulfonic acid; N-ethyl-N,N-diisopropylamine; In 1-methyl-pyrrolidin-2-one;
DOI:10.1021/jm0605482