3-(1H-Indol-7-yl)prop-2-enoic acid

Base Information

Chemical Name:3-(1H-Indol-7-yl)prop-2-enoic acid
CAS No.:288371-43-7
Molecular Formula:C₁₁H₉NO₂
Molecular Weight:187.198
Hs Code.:
DSSTox Substance ID:DTXSID50694938
Mol file:288371-43-7.mol

Synonyms:3-(1H-Indol-7-yl)prop-2-enoic acid;3-(1H-INDOL-7-YL)-ACRYLIC ACID;DTXSID50694938;ZLIDDFODQOEXPA-UHFFFAOYSA-N

Suppliers and Price of 3-(1H-Indol-7-yl)prop-2-enoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
3-(1H-indol-7-yl)acrylicacid 95
25g
$ 3447.00

Crysdot
(E)-3-(1H-Indol-7-yl)acrylicacid 95+%
1g
$ 455.00

Chemenu
(E)-3-(1H-indol-7-yl)acrylicacid 95%
1g
$ 430.00

American Custom Chemicals Corporation
(E)-3-(1H-INDOL-7-YL)ACRYLIC ACID 95.00%
5MG
$ 496.09

Alichem
(E)-3-(1H-Indol-7-yl)acrylicacid
1g
$ 379.44

Total 10 raw suppliers

Chemical Property of 3-(1H-Indol-7-yl)prop-2-enoic acid

Chemical Property:

PSA：53.09000
LogP:2.26570
Storage Temp.:2-8°C
XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:187.063328530
Heavy Atom Count:14
Complexity:250

Purity/Quality:

97% ^*data from raw suppliers

3-(1H-indol-7-yl)acrylicacid 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C(=C1)C=CC(=O)O)NC=C2

Technology Process of 3-(1H-Indol-7-yl)prop-2-enoic acid

There total 4 articles about 3-(1H-Indol-7-yl)prop-2-enoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 89976-15-8
7-iodo-1H-indole

: 79-10-7
acrylic acid

: 288371-43-7
(E)-3-(1H-indol-7-yl)acrylic acid

Guidance literature:: With sodium 2'‐(dicyclohexylphosphaneyl)‐2,6‐diisopropyl‐[1,1'‐biphenyl]‐3‐sulfonate; sodium tetrachloropalladate; sodium carbonate; In water; acetonitrile; at 80 ℃; for 1h; Inert atmosphere; Microwave irradiation;
DOI:10.1002/chem.201901327

Reference yield: 89.0%

: 51417-51-7
7-bromo-1H-indole

: 79-10-7
acrylic acid

: 288371-43-7
(E)-3-(1H-indol-7-yl)acrylic acid

Guidance literature:: With sodium 2'‐(dicyclohexylphosphaneyl)‐2,6‐diisopropyl‐[1,1'‐biphenyl]‐3‐sulfonate; sodium tetrachloropalladate; sodium carbonate; In water; acetonitrile; at 80 ℃; for 1h; Inert atmosphere; Microwave irradiation;
DOI:10.1002/chem.201901327

Reference yield: 87.0%

: 104682-97-5
methyl 3-(indol-7-yl)acrylate

: 288371-43-7
(E)-3-(1H-indol-7-yl)acrylic acid

Guidance literature:: methyl (E)-3-(1H-indol-7-yl)acrylate; With lithium hydroxide; water; In tetrahydrofuran; at 20 ℃; for 18h;

With hydrogenchloride; In tetrahydrofuran; water; at 0 ℃; pH=2;