2-AMino-5-iodobenzophenone

Base Information

• Chemical Name: 2-AMino-5-iodobenzophenone
• CAS No.: 51073-69-9
• Molecular Formula: C13H10INO
• Molecular Weight: 323.133
• Mol file: 51073-69-9.mol

Synonyms:2-amino-5-iodo-6-propyl-3H-pyrimidin-4-one;;2-Amino-5-iod-6-n-propyl-4-pyrimidinol;;2-Amino-5-iod-6-propyl-4-pyrimidinol;;2-amino-5-iodo-6-n-propyl-4-pyrimidinol;;2-Amino-5-iodo-6-propyl-4(3H)-pyrimidinone;;

Chemical Property of 2-AMino-5-iodobenzophenone

Chemical Property:

• Melting Point: 223-225 oC
• Boiling Point: 458.2±40.0 °C(Predicted)
• PKA: -0.10±0.10(Predicted)
• PSA: 43.09000
• Density: 1.683
• LogP: 3.68560

Purity/Quality:

98%Min ^*data from raw suppliers

2-Amino-5-iodobenzophenone 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-AMino-5-iodobenzophenone

There total 12 articles about 2-AMino-5-iodobenzophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(2-aminophenyl)(phenyl)methanone (2835-77-0) → (2-amino-5-iodophenyl)(phenyl)methanone (51073-69-9)

Guidance literature:

With tert.-butylhydroperoxide; iodine; In diethyl ether; at 80 ℃; for 18h;

DOI:10.1039/c1cc12885j

Reference yield: 70.6%

5-iodo-3-phenyl-2.1-benzoisoxazole (100675-76-1) → (2-amino-5-iodophenyl)(phenyl)methanone (51073-69-9)

Guidance literature:

With iron; acetic acid; at 55 ℃; for 0.5h;

DOI:10.1021/jm00126a003

Reference yield: 62.0%

C13H10INO4S → (2-amino-5-iodophenyl)(phenyl)methanone (51073-69-9)

Guidance literature:

With dipotassium hydrogenphosphate; [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-N1,N1′]bis{3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-κN]phenyl-κC}iridium(III) hexafluorophosphate; triphenylphosphine; In 1,4-dioxane; at 25 ℃; for 8h; Schlenk technique; Inert atmosphere; Sealed tube; Irradiation;

DOI:10.1002/chem.201903816

upstream raw materials:

5-iodo-3-phenyl-2.1-benzoisoxazole

phenyllithium

2-amino-5-iodobenzoic acid

p-nitrobenzene iodide

Downstream raw materials:

N-(2-Benzoyl-4-iodo-phenyl)-2-bromo-acetamide

7-iodo-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one

1,3-dihydro-7-iodo-5-phenyl-2H-1,4-benzodiazepine-2-thione

8-Iodo-6-phenyl-1-(phenylmethyl)-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine