5-Bromo-2,3-difluorobenzoic acid

Base Information

• Chemical Name: 5-Bromo-2,3-difluorobenzoic acid
• CAS No.: 887585-64-0
• Molecular Formula: C7H3BrF2O2
• Molecular Weight: 237
• Hs Code.: 2916399090
• Mol file: 887585-64-0.mol

Synonyms:5-BROMO-2,3-DIFLUOROBENZOIC ACID;Benzoic acid, 5-bromo-2,3-difluoro-

Chemical Property of 5-Bromo-2,3-difluorobenzoic acid

Chemical Property:

• PSA: 37.30000
• LogP: 2.42550
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

5-Bromo-2,3-difluorobenzoic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-Bromo-2,3-difluorobenzoic acid

There total 1 articles about 5-Bromo-2,3-difluorobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 2.0%

2,3-difluorobenzoic acid (4519-39-5) → 5-bromo-2,3-difluorobenzoic acid (887585-64-0)

Guidance literature:

With N-Bromosuccinimide; sulfuric acid; at 60 ℃; for 3h; Inert atmosphere;

Reference yield: 100.0%

oxalyl dichloride (79-37-8) + 5-bromo-2,3-difluorobenzoic acid (887585-64-0) + N,O-dimethylhydroxylamine*hydrochloride (6638-79-5) → 5-bromo-2,3-difluoro-N-methoxy-N-methylbenzamide (1600511-62-3)

Guidance literature:

With dmap; triethanolamine;

Reference yield: 97.0%

5-bromo-2,3-difluorobenzoic acid (887585-64-0) → 5-bromo-2,3-difluorobenzamide

Guidance literature:

5-bromo-2,3-difluorobenzoic acid; With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; for 2.5h; Inert atmosphere;

With ammonium hydroxide; In acetonitrile; at 20 ℃; for 0.25h; Inert atmosphere;

upstream raw materials:

2,3-difluorobenzoic acid

Downstream raw materials:

1-(5-bromo-2,3-difluorophenyl)ethanone

(E)-N-(1-(5-bromo-2,3-difluorophenyl)ethylidene)-2-methylpropane-2-sulfinamide

N-(2-(5-bromo-2,3-difluorophenyl)-1-((2-cyanopropan-2-yl)sulfonyl)propan-2-yl)-2-methylpropane-2-sulfinamide

5-bromo-2,3-difluoro-N-methoxy-N-methylbenzamide