5-(2-THIENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE

Base Information

Chemical Name:5-(2-THIENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE
CAS No.:26974-16-3
Molecular Formula:C8H5F3N2S
Molecular Weight:218.202
Hs Code.:2934999090
Mol file:26974-16-3.mol

Synonyms:5-(THIEN-2-YL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE;3-trifluoromethyl-5-(2-thienyl)pyrazole;5-(Trifluoromethyl)-3-(2-thienyl)-1H-pyrazole;1H-3-trifluoromethyl-5-(2-thienyl)-pyrazole;3(5)-trifluoromethyl-5(3)-(2-thienyl)-pyrazole;5-(2-THIENYL)-3-(TRIFLUOROMETHYL)PYRAZOLE;5-(thiophen-2-yl)-3-(trifluoromethyl)-1H-pyrazole;

Suppliers and Price of 5-(2-THIENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-(2-thienyl)-3-(trifluoromethyl)-1H-pyrazole
100mg
$ 65.00

American Custom Chemicals Corporation
5-(2-THIENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE 95.00%
1G
$ 1215.06

Total 14 raw suppliers

Chemical Property of 5-(2-THIENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE

Chemical Property:

Vapor Pressure:0.000229mmHg at 25°C
Melting Point:120-122oC
Boiling Point:335.7oC at 760 mmHg
Flash Point:156.8oC
PSA：56.92000
Density:1.461g/cm3
LogP:3.15700

Purity/Quality:

97% ^*data from raw suppliers

5-(2-thienyl)-3-(trifluoromethyl)-1H-pyrazole ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-(2-THIENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE

There total 7 articles about 5-(2-THIENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 128228-95-5
3-trifluoromethyl-5-(2-thienyl)-pyrazol-1-thiocarboxamide

: 26974-16-3
5-(thiophen-2-yl)-3-(trifluoromethyl)-1H-pyrazole

Guidance literature:: In ethanol; for 3h; Heating;

Reference yield: 81.0%

: 326-91-0
1,1,1-trifluoro-4-(2-thienyl)butane-2,4-dione

: 26974-16-3
5-(thiophen-2-yl)-3-(trifluoromethyl)-1H-pyrazole

Guidance literature:: 1,1,1-trifluoro-4-(2-thienyl)butane-2,4-dione; With hydrazine hydrate; In ethanol; Reflux;

With hydrogenchloride; water; for 0.0166667h; Reflux;
DOI:10.1016/j.tet.2012.10.034

Reference yield: 78.0%

: 98-03-3
thiophene-2-carbaldehyde

: 1514-82-5
2-bromo-3,3,3-trifluoropropene

: 26974-16-3
5-(thiophen-2-yl)-3-(trifluoromethyl)-1H-pyrazole

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; toluene-4-sulfonic acid hydrazide; In toluene; at 60 ℃; for 6h; regioselective reaction;
DOI:10.1021/acs.orglett.9b04228