4-Bromo-2,6-dichlorobenzoic acid

Base Information

• Chemical Name: 4-Bromo-2,6-dichlorobenzoic acid
• CAS No.: 232275-51-3
• Molecular Formula: C7H3BrCl2O2
• Molecular Weight: 269.91
• Hs Code.: 2916399090
• Mol file: 232275-51-3.mol

Synonyms:4-BROMO-2,6-DICHLOROBENZOIC ACID;Benzoic acid, 4-broMo-2,6-dichloro-

Chemical Property of 4-Bromo-2,6-dichlorobenzoic acid

Chemical Property:

• Melting Point: 165.0 to 169.0 °C
• PSA: 37.30000
• Density: 1.900
• LogP: 3.45410
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

4-Bromo-2,6-dichlorobenzoic Acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Bromo-2,6-dichlorobenzoic acid

There total 13 articles about 4-Bromo-2,6-dichlorobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

methyl 4-bromo-2,6-dichlorobenzoate (232275-53-5) → 4-bromo-2,6-dichloro-benzoic acid (232275-51-3)

Guidance literature:

With lithium hydroxide; In tetrahydrofuran; methanol; for 24h; Heating;

DOI:10.1016/S0968-0896(02)00021-4

Reference yield: 42.0%

3-amino-4-bromo-2,6-dichlorobenzoic acid (1415124-69-4) → 4-bromo-2,6-dichloro-benzoic acid (232275-51-3)

Guidance literature:

3-amino-4-bromo-2,6-dichlorobenzoic acid; With hydrogenchloride; sodium nitrite; In water; at -10 - -5 ℃; for 2h;

With hypophosphorous acid; In water; at -10 - -5 ℃; for 4h;

Reference yield:

1,3-dichloro-2-methyl-5-nitrobenzene (7149-69-1) → C7H2Br2Cl2O2 + 4-bromo-2,6-dichloro-benzoic acid (232275-51-3)

Guidance literature:

Multi-step reaction with 3 steps

1.1: potassium permanganate; pyridine / water / 100 °C

2.1: sulfuric acid / 4 h / Reflux

2.2: Reflux

3.1: hydrogen bromide; sodium nitrite / 1 h / -10 - -5 °C

3.2: Reflux

3.3: 10 h / 50 °C

With pyridine; potassium permanganate; sulfuric acid; hydrogen bromide; sodium nitrite; In water;

upstream raw materials:

methyl 4-bromo-2,6-dichlorobenzoate

2,6-dichloro-4-nitrobenzoic acid

methyl 2,6-dichloro-4-nitrobenzoate

methyl 4-amino-2,6-dichlorobenzoate

Downstream raw materials:

N-{3-[2,6-dichloro-4-(3,5-dimethyl-1,2-oxazol-4-yl)benzoyl]-1H-pyrrolo[2,3-c]pyridin-7-yl}cyclopropanecarboxamide

N-[3-(4-bromo-2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-c]pyridin-7-yl]cyclopropanecarboxamide

N-{3-[2,6-dichloro-4-(pyrimidin-5-yl)benzoyl]-1H-pyrrolo[2,3-c]pyridin-7-yl}cyclopropanecarboxamide

N-[3-(4-amino-2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-c]pyridin-7-yl]cyclopropanecarboxamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 232275-51-3 4-Bromo-2,6-dichlorobenzoic acid

Send

Send

Metric Ton KG G Pound L ML

Send

Send