1-Bromo-4-fluoro-5-isopropyl-2-methoxybenzene

Base Information

• Chemical Name: 1-Bromo-4-fluoro-5-isopropyl-2-methoxybenzene
• CAS No.: 944317-92-4
• Molecular Formula: C10H12BrFO
• Molecular Weight: 247.107
• Hs Code.: 2909309090
• Mol file: 944317-92-4.mol

Synonyms:1-BroMo-4-fluoro-5-isopropyl-2-Methoxybenzene;1-BroMo-4-fluoro-5-isopro...;Benzene, 1-broMo-4-fluoro-2-Methoxy-5-(1-Methylethyl)-

Chemical Property of 1-Bromo-4-fluoro-5-isopropyl-2-methoxybenzene

Chemical Property:

• Boiling Point: 240.1±40.0℃ (760 Torr)
• Flash Point: 124.3±11.6℃
• PSA: 9.23000
• Density: 1.343±0.06 g/cm3 (20 oC 760 Torr)
• LogP: 3.72020
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

1-Bromo-4-fluoro-5-isopropyl-2-methoxybenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Bromo-4-fluoro-5-isopropyl-2-methoxybenzene

There total 14 articles about 1-Bromo-4-fluoro-5-isopropyl-2-methoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.19%

2-(2-fluoro-4-methoxyphenyl)isopropane (1262414-96-9) → 1-bromo-4-fluoro-2-methoxy-5-(propan-2-yl)-benzene (944317-92-4)

Guidance literature:

With N-Bromosuccinimide; In acetonitrile; at 28 - 35 ℃; for 6h; Time;

Reference yield: 98.0%

1-bromo-4-fluoro-2-methoxy-5-(1-methylvinyl)benzene (1383814-82-1) → 1-bromo-4-fluoro-2-methoxy-5-(propan-2-yl)-benzene (944317-92-4)

Guidance literature:

With hydrogen bromide; hydrogen; 5%-palladium/activated carbon; In methanol; water; at 20 ℃; for 0.25h; under 3102.97 Torr; Product distribution / selectivity; Inert atmosphere;

Reference yield: 91.0%

2-fluoro-4-methoxy-1-(prop-1-en-2-yl)benzene (875446-55-2) + 2-(2-fluoro-4-methoxyphenyl)-2-isopropanol (96826-25-4) → 1-bromo-4-fluoro-2-methoxy-5-(propan-2-yl)-benzene (944317-92-4)

Guidance literature:

2-fluoro-4-methoxy-1-(prop-1-en-2-yl)benzene; 2-(2-fluoro-4-methoxyphenyl)-2-isopropanol; With hydrogen; palladium on activated carbon; In methanol; at 50 ℃; under 2250.23 Torr; Inert atmosphere;

With 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione; In methanol; at 40 ℃;

upstream raw materials:

2-(2-fluoro-4-methoxyphenyl)isopropane

1-(5-bromo-2-fluoro-4-methoxyphenyl)ethan-1-one

2-(5-bromo-2-fluoro-4-methoxyphenyl)propan-2-ol

2,4-difluorobromobenzene

Downstream raw materials:

(4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)-[1,1'-biphenyl]-2-yl)methanol

2'-(bromomethyl)-4-fluoro-2-methoxy-5-(propan-2-yl)-4'-(trifluoromethyl)biphenyl

5-(3,5-bis(trifluoromethyl)phenyl)-3-((4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl)methyl)-4-methylthiazolidin-2-one

anacetrapib

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 944317-92-4 1-Bromo-4-fluoro-5-isopropyl-2-methoxybenzene

Send

Send

Metric Ton KG G Pound L ML

Send

Send