N-(3-Methoxy-4-nitrophenyl)acetamide

Base Information

• Chemical Name: N-(3-Methoxy-4-nitrophenyl)acetamide
• CAS No.: 20628-19-7
• Molecular Formula: C9H10N2O4
• Molecular Weight: 210.189
• Hs Code.: 2924299090
• DSSTox Substance ID: DTXSID50547950
• Nikkaji Number: J154.697J
• Wikidata: Q82426501
• Mol file: 20628-19-7.mol

Synonyms:N-(3-Methoxy-4-nitrophenyl)acetamide;20628-19-7;N-(3-methoxy-4-nitro-phenyl)-acetamide;C9H10N2O4;SCHEMBL359321;DTXSID50547950;AMY24025;CS-M0191;AKOS005067137;DS-2555;I11077;A879527

Chemical Property of N-(3-Methoxy-4-nitrophenyl)acetamide

Chemical Property:

• PSA: 87.64000
• LogP: 2.73450
• Storage Temp.: 2-8°C
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 210.06405680
• Heavy Atom Count: 15
• Complexity: 251

Purity/Quality:

97% ^*data from raw suppliers

N-(3-Methoxy-4-nitrophenyl)acetamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NC1=CC(=C(C=C1)[N+](=O)[O-])OC

Technology Process of N-(3-Methoxy-4-nitrophenyl)acetamide

There total 9 articles about N-(3-Methoxy-4-nitrophenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

m-methoxyacetanilide (588-16-9) → N-(3-methoxy-4-nitrophenyl)acetamide (20628-19-7)

Guidance literature:

With nitric acid; In acetic acid; at 0 - 20 ℃;

DOI:10.1002/chem.200901322

Reference yield: 46.0%

m-methoxyacetanilide (588-16-9) → N-(3-methoxy-4-nitrophenyl)acetamide (20628-19-7) + 1-acetamido-5-methoxy-2nitrobenzene (20628-18-6)

Guidance literature:

With nitric acid; acetic anhydride;

DOI:10.1002/jhet.5570320523

Reference yield:

3-hydroxy-4-nitroacetanilide (712-34-5) + methyl iodide (74-88-4) → N-(3-methoxy-4-nitrophenyl)acetamide (20628-19-7)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 2h;

upstream raw materials:

m-methoxyacetanilide

m-Anisidine

3-hydroxy-4-nitroacetanilide

methyl iodide

Downstream raw materials:

3-methoxy-4-nitro-N-(methylsulfonyl)benzenamine

N-(4-amino-3-methoxyphenyl)methanesulfonamide

9-(4-Methanesulfonylamino-2-methoxy-phenylamino)-5-methyl-acridine-4-carboxylic acid methylamide; hydrochloride

N-[4-(9-acridinylamino)-3-methoxyphenyl]methanesulfonamide hcrochloride