3-Methoxy-4-(trifluoromethyl)aniline

Base Information

Chemical Name:3-Methoxy-4-(trifluoromethyl)aniline
CAS No.:106877-20-7
Molecular Formula:C8H8F3NO
Molecular Weight:191.153
Hs Code.:2922299090
European Community (EC) Number:830-105-4
DSSTox Substance ID:DTXSID30548364
Wikidata:Q82427058
Mol file:106877-20-7.mol

Synonyms:3-Methoxy-4-(trifluoromethyl)aniline;106877-20-7;3-methoxy-4-(trifluoromethyl)phenylamine;3-METHOXY-4-TRIFLUOROMETHYLANILINE;MFCD11840978;Benzenamine, 3-methoxy-4-(trifluoromethyl)-;SCHEMBL1013276;DTXSID30548364;CL8432;AKOS005071643;AD-0769;CS-W021951;3-methoxy-4-trifluoromethyl-phenylamine;SY105261;EN300-106574;A895733;J-512760;Z1201625815

Suppliers and Price of 3-Methoxy-4-(trifluoromethyl)aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Methoxy-4-(trifluoromethyl)aniline
500mg
$ 175.00

Matrix Scientific
3-Methoxy-4-(trifluoromethyl)phenylamine >95%
5g
$ 600.00

Matrix Scientific
3-Methoxy-4-(trifluoromethyl)phenylamine >95%
500mg
$ 155.00

Matrix Scientific
3-Methoxy-4-(trifluoromethyl)phenylamine >95%
1g
$ 230.00

Crysdot
3-Methoxy-4-(trifluoromethyl)aniline 98%
5g
$ 297.00

Crysdot
3-Methoxy-4-(trifluoromethyl)aniline 98%
10g
$ 475.00

Chemenu
3-Methoxy-4-(trifluoromethyl)aniline 95+%
10g
$ 449.00

Chemenu
3-Methoxy-4-(trifluoromethyl)aniline 95+%
5g
$ 281.00

Apolloscientific
3-Methoxy-4-(trifluoromethyl)aniline
1g
$ 115.00

American Custom Chemicals Corporation
3-METHOXY-4-(TRIFLUOROMETHYL)ANILINE 95.00%
5MG
$ 495.35

Total 20 raw suppliers

Chemical Property of 3-Methoxy-4-(trifluoromethyl)aniline

Chemical Property:

Vapor Pressure:0.0±0.5 mmHg at 25°C
Melting Point:49-50°
Boiling Point:257.0±40.0 °C at 760 mmHg
Flash Point:109.3±27.3 °C
PSA：35.25000
Density:1.3±0.1 g/cm3
LogP:2.87740
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:191.05579836
Heavy Atom Count:13
Complexity:171

Purity/Quality:

97% ^*data from raw suppliers

3-Methoxy-4-(trifluoromethyl)aniline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=CC(=C1)N)C(F)(F)F

Technology Process of 3-Methoxy-4-(trifluoromethyl)aniline

There total 8 articles about 3-Methoxy-4-(trifluoromethyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 453560-74-2
2-methoxy-4-nitro-1-(trifluoromethyl)benzene

: 106877-20-7
3-methoxy-4-(trifluoromethyl)aniline

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In ethanol; at 55 ℃; for 18h; under 2947.82 Torr; Inert atmosphere;
DOI:10.1021/jm401329s

Reference yield: 93.0%

: C₁₃H₁₆F₃NO₃

: 106877-20-7
3-methoxy-4-(trifluoromethyl)aniline

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1.5h;
DOI:10.1021/acs.jmedchem.9b01429

Reference yield: 23.0%

: 887144-94-7
Togni's reagent II

: 536-90-3,918666-97-4
m-Anisidine

: 654-83-1
5-methoxy-2-(trifluoromethyl)aniline

: 106877-20-7
3-methoxy-4-(trifluoromethyl)aniline

: 53982-03-9
3-methoxy-2-(trifluoromethyl)aniline

Guidance literature:: With potassium carbonate; nickel(II) hydroxide; In dimethyl sulfoxide; at 35 ℃; for 2h; Inert atmosphere;
DOI:10.1021/acs.orglett.8b01216