methyl (1S,3S,6R,8S)-3-phenyl-2,4,7-trioxabicyclo[4.2.0]octane-8-carboxylate

Base Information

Chemical Name:methyl (1S,3S,6R,8S)-3-phenyl-2,4,7-trioxabicyclo[4.2.0]octane-8-carboxylate
CAS No.:131550-06-6
Molecular Formula:C13H14O5
Molecular Weight:250.25
Hs Code.:
European Community (EC) Number:830-889-8
Nikkaji Number:J1.521.440F
Mol file:131550-06-6.mol

Synonyms:131550-06-6;methyl (1S,3S,6R,8S)-3-phenyl-2,4,7-trioxabicyclo[4.2.0]octane-8-carboxylate;2,4-Anhydro-3,5-O-[(S)-phenylmethylene]-D-lyxonic acid methyl ester;CS-0100739;EN300-6499882;A897961

Suppliers and Price of methyl (1S,3S,6R,8S)-3-phenyl-2,4,7-trioxabicyclo[4.2.0]octane-8-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of methyl (1S,3S,6R,8S)-3-phenyl-2,4,7-trioxabicyclo[4.2.0]octane-8-carboxylate

Chemical Property:

PSA：53.99000
LogP:1.04100
XLogP3:1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:250.08412354
Heavy Atom Count:18
Complexity:313

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1C2C(O1)COC(O2)C3=CC=CC=C3
Isomeric SMILES:COC(=O)[C@@H]1[C@@H]2[C@H](O1)CO[C@@H](O2)C3=CC=CC=C3

Technology Process of methyl (1S,3S,6R,8S)-3-phenyl-2,4,7-trioxabicyclo[4.2.0]octane-8-carboxylate

There total 15 articles about methyl (1S,3S,6R,8S)-3-phenyl-2,4,7-trioxabicyclo[4.2.0]octane-8-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 67-56-1
methanol

: 130481-72-0
(S)-3,5-O-benzylidene-2-O-trifluoromethanesulfonyl-D-xylono-1,4-lactone

: 131550-06-6
methyl 2,4-anhydro-(S)-3,5-benzylidene-D-lyxonate

Guidance literature:: With potassium carbonate;
DOI:10.1016/S0957-4166(00)80541-8

Reference yield: 38.0%

: 67-56-1
methanol

: 130481-71-9
Trifluoro-methanesulfonic acid (2S,4aR,7S,7aS)-6-oxo-2-phenyl-tetrahydro-furo[3,2-d][1,3]dioxin-7-yl ester

: 131550-06-6
methyl 2,4-anhydro-(S)-3,5-benzylidene-D-lyxonate

Guidance literature:: With potassium carbonate;
DOI:10.1016/S0957-4166(00)80541-8

Reference yield:

: 131614-83-0
(2S,4aR,7R,7aR)-7-hydroxy-2-phenyltetrahydro-6H-furo[3,2-d][1,3]dioxin-6-one

: 131550-06-6
methyl 2,4-anhydro-(S)-3,5-benzylidene-D-lyxonate

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / pyridine / CH₂Cl₂ / 2.25 h / -30 - -10 °C

2: 75 percent / potassium carbonate / 4 h / -25 - -20 °C

With pyridine; potassium carbonate; In dichloromethane;
DOI:10.1016/j.tetasy.2004.07.031