FMoc-(2S,3R)-2-aMino-3-hydroxy-4-Methylpentanoic acid

Base Information

Chemical Name:FMoc-(2S,3R)-2-aMino-3-hydroxy-4-Methylpentanoic acid
CAS No.:940301-35-9
Molecular Formula:C21H23NO5
Molecular Weight:369.41
Hs Code.:
Mol file:940301-35-9.mol

Synonyms:(2S,3R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxy-4-methylpentanoic acid;FMOC-(2S,3R)-2-AMINO-3-HYDROXY-4-METHYLPENTANOIC ACID;

Suppliers and Price of FMoc-(2S,3R)-2-aMino-3-hydroxy-4-Methylpentanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(2S,3R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxy-4-methylpentanoicacid 95+%
100mg
$ 304.00

Crysdot
(2S,3R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxy-4-methylpentanoicacid 95+%
250mg
$ 485.00

Crysdot
(2S,3R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxy-4-methylpentanoicacid 95+%
1g
$ 1214.00

Chemenu
(2S,3R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxy-4-methylpentanoicacid 95%
1g
$ 1146.00

American Custom Chemicals Corporation
FMOC-(2S,3R)-2-AMINO-3-HYDROXY-4-METHYLPENTANOIC ACID 95.00%
5MG
$ 505.36

Ambeed
(2S,3R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxy-4-methylpentanoicacid 98+%
250mg
$ 371.00

Ambeed
(2S,3R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxy-4-methylpentanoicacid 98+%
100mg
$ 232.00

Ambeed
(2S,3R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxy-4-methylpentanoicacid 98+%
1g
$ 898.00

Activate Scientific
(2S,3R)-2-(Fmoc-amino)-3-hydroxy-4-methylpentanoicacid 98+%
1 g
$ 1527.00

Activate Scientific
(2S,3R)-2-(Fmoc-amino)-3-hydroxy-4-methylpentanoicacid 98+%
250 mg
$ 636.00

Total 8 raw suppliers

Chemical Property of FMoc-(2S,3R)-2-aMino-3-hydroxy-4-Methylpentanoic acid

Chemical Property:

Boiling Point:601.8±55.0 °C(Predicted)
PKA:3.51±0.23(Predicted)
PSA：95.86000
Density:1.271±0.06 g/cm3(Predicted)
LogP:3.38610
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

(2S,3R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxy-4-methylpentanoicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of FMoc-(2S,3R)-2-aMino-3-hydroxy-4-Methylpentanoic acid

There total 3 articles about FMoc-(2S,3R)-2-aMino-3-hydroxy-4-Methylpentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 5817-22-1,6645-45-0,10148-70-6,28908-11-4,35016-54-7,35016-62-7,87421-23-6,87421-24-7,10148-71-7
(2S,3R)-3-hydroxyleucine

: 102774-86-7
9-fluorenylmethyl N-succinimidyl carbonate

: 940301-35-9,1217833-77-6,1217516-81-8
(2S,3R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino-3-hydroxy-4-methyl)pentanoic acid

Guidance literature:: With sodium carbonate; In water; at 20 ℃; for 24h; Inert atmosphere;
DOI:10.1021/ol503507g

Reference yield: 48.0%

: 5817-22-1,6645-45-0,10148-70-6,28908-11-4,35016-54-7,35016-62-7,87421-23-6,87421-24-7,10148-71-7
(2S,3R)-3-hydroxyleucine

: 28920-43-6
(fluorenylmethoxy)carbonyl chloride

: 940301-35-9,1217833-77-6,1217516-81-8
(2S,3R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino-3-hydroxy-4-methyl)pentanoic acid

Guidance literature:: (2S,3R)-3-hydroxyleucine; With N,O-bis-(trimethylsilyl)-acetamide; In dichloromethane; at 20 ℃; for 2.25h;

(fluorenylmethoxy)carbonyl chloride; With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 20 ℃; for 5.5h;
DOI:10.1002/cmdc.201800304