Ethyl 4-methylpyrazolo[1,5-a]pyridine-3-carboxylate

Base Information

Chemical Name:Ethyl 4-methylpyrazolo[1,5-a]pyridine-3-carboxylate
CAS No.:55899-17-7
Molecular Formula:
Molecular Weight:0
Hs Code.:
DSSTox Substance ID:DTXSID001225219

Synonyms:ethyl 4-methylpyrazolo[1,5-a]pyridine-3-carboxylate;55899-17-7;DTXSID001225219;ethyl4-methylpyrazolo[1,5-a]pyridine-3-carboxylate

Suppliers and Price of Ethyl 4-methylpyrazolo[1,5-a]pyridine-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Ethyl 4-methylpyrazolo[1,5-a]pyridine-3-carboxylate

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:204.089877630
Heavy Atom Count:15
Complexity:245

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C2C(=CC=CN2N=C1)C

Technology Process of Ethyl 4-methylpyrazolo[1,5-a]pyridine-3-carboxylate

There total 4 articles about Ethyl 4-methylpyrazolo[1,5-a]pyridine-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

: 7583-91-7
1-amino-3-methylpyridin-1-ium iodide

: 623-47-2
propynoic acid ethyl ester

: 55899-17-7
ethyl 4-methylpyrazolo[1,5-a]pyridine-3-carboxylate

: 55899-18-8
ethyl 6-methylpyrazolo[1,5-a]pyridine-3-carboxylate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1016/j.bmcl.2011.05.126

Reference yield: 21.0%

: 108-99-6
3-Methylpyridine

: 623-47-2
propynoic acid ethyl ester

: 55899-17-7
ethyl 4-methylpyrazolo[1,5-a]pyridine-3-carboxylate

: 55899-18-8
ethyl 6-methylpyrazolo[1,5-a]pyridine-3-carboxylate

Guidance literature:: 3-Methylpyridine; With mesitylenesulfonylhydroxylamine; In dichloromethane; at 0 ℃; for 2h;

propynoic acid ethyl ester; With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 18h;
DOI:10.1016/j.bmc.2011.11.029

Reference yield:

: 108-99-6
3-Methylpyridine

: 55899-17-7
ethyl 4-methylpyrazolo[1,5-a]pyridine-3-carboxylate

: 55899-18-8
ethyl 6-methylpyrazolo[1,5-a]pyridine-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogen iodide; hydroxylamine-O-sulfonic acid / water / 20 - 87 °C

2: potassium carbonate / N,N-dimethyl-formamide / 20 °C

With hydrogen iodide; potassium carbonate; hydroxylamine-O-sulfonic acid; In water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2011.05.126