3-[(E)-[5-(4-nitrophenyl)furan-2-yl]methylideneamino]-2-oxo-4H-imidazol-5-olate

Base Information

Chemical Name:3-[(E)-[5-(4-nitrophenyl)furan-2-yl]methylideneamino]-2-oxo-4H-imidazol-5-olate
CAS No.:7261-97-4
Molecular Formula:C14H10 N4 O5
Molecular Weight:314.257
Hs Code.:2934990002
European Community (EC) Number:230-684-8
Wikipedia:Dantrolene
NCI Thesaurus Code:C61697,C61698
RXCUI:3105,3106
Mol file:7261-97-4.mol

Synonyms:Dantrium;Dantrolene;Dantrolene Sodium;Sodium, Dantrolene

Suppliers and Price of 3-[(E)-[5-(4-nitrophenyl)furan-2-yl]methylideneamino]-2-oxo-4H-imidazol-5-olate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Dantrolene
100mg
$ 215.00

Sigma-Aldrich
Dantrolene PharmaceuticalSecondaryStandard;CertifiedReferenceMaterial
500MG
$ 139.00

Sigma-Aldrich
Dantrolene
200mg
$ 381.00

Medical Isotopes, Inc.
Dantrolene
25 mg
$ 1500.00

AvaChem
Dantrolene
1g
$ 279.00

AvaChem
Dantrolene
100mg
$ 49.00

American Custom Chemicals Corporation
DANTROLENE 95.00%
1G
$ 745.50

Ambeed
1-(((5-(4-Nitrophenyl)furan-2-yl)methylene)amino)imidazolidine-2,4-dione 98+%
5g
$ 280.00

Ambeed
1-(((5-(4-Nitrophenyl)furan-2-yl)methylene)amino)imidazolidine-2,4-dione 98+%
1g
$ 77.00

Ambeed
1-(((5-(4-Nitrophenyl)furan-2-yl)methylene)amino)imidazolidine-2,4-dione 98+%
250mg
$ 31.00

Total 27 raw suppliers

Chemical Property of 3-[(E)-[5-(4-nitrophenyl)furan-2-yl]methylideneamino]-2-oxo-4H-imidazol-5-olate

Chemical Property:

Melting Point:279-280°
Refractive Index:1.6000 (estimate)
Boiling Point:453.94°C (rough estimate)
PKA:7.68±0.10(Predicted)
PSA：120.73000
Density:1.57 g/cm³
LogP:2.53040
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:313.05729440
Heavy Atom Count:23
Complexity:536

Purity/Quality:

98% ^*data from raw suppliers

Dantrolene ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Drug Classes:Autonomic Agents: Muscle Relaxants, Central
Canonical SMILES:C1C(=NC(=O)N1N=CC2=CC=C(O2)C3=CC=C(C=C3)[N+](=O)[O-])[O-]
Isomeric SMILES:C1C(=NC(=O)N1/N=C/C2=CC=C(O2)C3=CC=C(C=C3)[N+](=O)[O-])[O-]
Recent ClinicalTrials:A Clinical Trial of Dantrolene Sodium in Pediatric and Adult Patients With Wolfram Syndrome
Uses Dantrolene acts as a skeletal muscle relaxant through inhibition of Ca2+ release through ryanodine receptor channels.
Therapeutic Function Muscle relaxant

Technology Process of 3-[(E)-[5-(4-nitrophenyl)furan-2-yl]methylideneamino]-2-oxo-4H-imidazol-5-olate

There total 9 articles about 3-[(E)-[5-(4-nitrophenyl)furan-2-yl]methylideneamino]-2-oxo-4H-imidazol-5-olate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%