Swertiamarin

Base Information

Chemical Name:Swertiamarin
CAS No.:17388-39-5
Molecular Formula:C16H22O10
Molecular Weight:374.345
Hs Code.:29389090
UNII:4038595T7Y
DSSTox Substance ID:DTXSID50169676
Nikkaji Number:J10.346B
Wikidata:Q27108363
Metabolomics Workbench ID:69314
ChEMBL ID:CHEMBL456138
Mol file:17388-39-5.mol

Synonyms:swertiamarin;swertiamaroside

Suppliers and Price of Swertiamarin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Swertiamarin
50mg
$ 355.00

Usbiological
Swertiamarin
20mg
$ 320.00

TRC
Swertimarine
100mg
$ 220.00

TCI Chemical
Swertiamarin >98.0%(HPLC)
25mg
$ 211.00

Sigma-Aldrich
Swertiamarin analytical standard
10mg
$ 199.00

Sigma-Aldrich
Swertiamarin ≥95% (LC/MS-ELSD)
1mg
$ 247.00

Medical Isotopes, Inc.
Swertimarine
5 mg
$ 575.00

Medical Isotopes, Inc.
Swertimarine
100 mg
$ 700.00

DC Chemicals
Swertiamarine >98%
20 mg
$ 280.00

CSNpharm
Swertiamarine
25mg
$ 135.00

Total 114 raw suppliers

Chemical Property of Swertiamarin

Chemical Property:

Appearance/Colour:white powder
Vapor Pressure:1.32E-19mmHg at 25°C
Melting Point:111oC
Refractive Index:1.625
Boiling Point:649.3 °C at 760 mmHg
PKA:11.56±0.60(Predicted)
Flash Point:237.7 °C
PSA：155.14000
Density:1.57 g/cm³
LogP:-2.47670
Storage Temp.:?20°C
XLogP3:-2
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:4
Exact Mass:374.12129689
Heavy Atom Count:26
Complexity:592

Purity/Quality:

98%, ^*data from raw suppliers

Swertiamarin ^*data from reagent suppliers

Safty Information:

Pictogram(s): C
Hazard Codes:C
Safety Statements: 24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C=CC1C(OC=C2C1(CCOC2=O)O)OC3C(C(C(C(O3)CO)O)O)O
Isomeric SMILES:C=C[C@H]1[C@@H](OC=C2[C@]1(CCOC2=O)O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O
Uses Swertimarine is an extract from Enicostemma littorale which is an herb used in the treatment of type 1 and 2 diabetes. Used to sensitize the cells to hypolipidemic conditions and insulin.

Technology Process of Swertiamarin

There total 1 articles about Swertiamarin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2'-(2'',3''-dihydroxybenzoyl)swertiamarin

: 2411-83-8
methyl-2,3-dihydroxybenzoate

: 17388-39-5
swertiamarin

Guidance literature:: With sodium methylate; In methanol; at 20 ℃; for 3h;
DOI:10.1016/j.fitote.2013.08.006

Reference yield:

: 17388-39-5
swertiamarin

: 937-14-4
3-chloro-benzenecarboperoxoic acid

: C₁₇H₁₅ClO₆

Guidance literature:: at 37 ℃; for 24h; Inert atmosphere;
DOI:10.1080/14786419.2020.1825428

Reference yield:

: 67-56-1
methanol

: 17388-39-5
swertiamarin

: 5-(hydroxymethyl)-3,4-dihydro-1H-2-benzopyran-1-one

: 50276-98-7
5-formyl-2,3-dihydroisocoumarin

: 90921-13-4
1-oxo-isochroman-5-carboxylic acid

: 3,4,5,6-tetrahydro-8-hydroxy-6-methylpyrano[3,4-c]pyran-1(8H)-one

: sweritranslactone D

: sweritranslactone E

: swerimilegenin E

: swerimilegenin G

: C₁₀H₁₀O₄

Guidance literature:: swertiamarin; With water; for 6h; Reflux; Industrial scale;

methanol; In water; Industrial scale;
DOI:10.1016/j.fitote.2021.104879