2-chloro-7-Boc-7H-pyrrolo[2,3-D]pyriMidine

Base Information

Chemical Name:2-chloro-7-Boc-7H-pyrrolo[2,3-D]pyriMidine
CAS No.:1393648-54-8
Molecular Formula:C11H12ClN3O2
Molecular Weight:253.68488
Hs Code.:
Mol file:1393648-54-8.mol

Synonyms:2-chloro-7-Boc-7H-pyrrolo[2,3-D]pyriMidine;tert-butyl 2-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate

Suppliers and Price of 2-chloro-7-Boc-7H-pyrrolo[2,3-D]pyriMidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1,1-Dimethylethyl2-Chloro-7h-pyrrolo[2,3-D]pyrimidine-7-carboxylate
500mg
$ 240.00

Matrix Scientific
2-Chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylicacid1,1-dimethylethylester 95+%
1g
$ 364.00

Crysdot
2-Chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylicacid1,1-dimethylethylester 95+%
1g
$ 333.00

Chemenu
tert-butyl2-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate 95%+
10g
$ 1802.00

Chemenu
tert-butyl2-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate 95%+
5g
$ 1199.00

Chemenu
tert-butyl2-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate 95%+
1g
$ 399.00

Total 12 raw suppliers

Chemical Property of 2-chloro-7-Boc-7H-pyrrolo[2,3-D]pyriMidine

Chemical Property:

Purity/Quality:

99%, ^*data from raw suppliers

1,1-Dimethylethyl2-Chloro-7h-pyrrolo[2,3-D]pyrimidine-7-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-chloro-7-Boc-7H-pyrrolo[2,3-D]pyriMidine

There total 5 articles about 2-chloro-7-Boc-7H-pyrrolo[2,3-D]pyriMidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1038588-24-7
2,4-dichloropyrrolo[2,3-d]pyrimidine-7-carboxylic acid tert-butyl ester

: 1393648-54-8
tert-butyl 2-chloropyrrolo[2,3-d]pyrimidine-7-carboxylate

Guidance literature:: With palladium on activated charcoal; hydrogen; triethylamine; In ethanol;

Reference yield:

: 2,4-dichloro-6-iodo-7H-pyrrolo[2,3-d]pyrimidine

: 1393648-54-8
tert-butyl 2-chloropyrrolo[2,3-d]pyrimidine-7-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate; palladium on activated charcoal; hydrogen / ethanol / 4 h

2: dmap; triethylamine / ethanol / 0.5 h

3: palladium on activated charcoal; hydrogen; triethylamine / ethanol

With dmap; palladium on activated charcoal; hydrogen; potassium carbonate; triethylamine; In ethanol;

Reference yield:

: 2,6-dichloro-5-[2-trimethylsilylethynyl]pyrimidine-4-amine

: 1393648-54-8
tert-butyl 2-chloropyrrolo[2,3-d]pyrimidine-7-carboxylate

Guidance literature:: Multi-step reaction with 5 steps

1: silver nitrate; N-iodo-succinimide / N,N-dimethyl-formamide / 0.5 h / Cooling with ice

2: potassium tert-butylate; 18-crown-6 ether / 1-methyl-pyrrolidin-2-one / 0.07 h / 60 °C

3: potassium carbonate; palladium on activated charcoal; hydrogen / ethanol / 4 h

4: dmap; triethylamine / ethanol / 0.5 h

5: palladium on activated charcoal; hydrogen; triethylamine / ethanol

With dmap; N-iodo-succinimide; 18-crown-6 ether; palladium on activated charcoal; potassium tert-butylate; hydrogen; potassium carbonate; silver nitrate; triethylamine; In 1-methyl-pyrrolidin-2-one; ethanol; N,N-dimethyl-formamide;