4-(PhenoxyMethyl)benzeneboronic acid pinacol ester, 95%

Base Information

• Chemical Name: 4-(PhenoxyMethyl)benzeneboronic acid pinacol ester, 95%
• CAS No.: 946409-21-8
• Molecular Formula: C19H23BO3
• Molecular Weight: 310.2
• Mol file: 946409-21-8.mol

Synonyms:4-(PhenoxyMethyl)benzeneboronic acid pinacol ester, 95%

Chemical Property of 4-(PhenoxyMethyl)benzeneboronic acid pinacol ester, 95%

Chemical Property:

• PSA: 27.69000
• LogP: 3.56480

Purity/Quality:

99% ^*data from raw suppliers

4,4,5,5-Tetramethyl-2-(4-Phenoxymethyl-Phenyl)-[1,3,2]Dioxaborolane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(PhenoxyMethyl)benzeneboronic acid pinacol ester, 95%

There total 3 articles about 4-(PhenoxyMethyl)benzeneboronic acid pinacol ester, 95% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-bromomethylphenylboronic acid pinacol ester (138500-85-3) + phenol (108-95-2,27073-41-2) → C19H23BO3 (946409-21-8)

Guidance literature:

With tetrabutylammomium bromide; potassium carbonate; sodium hydroxide; at 110 ℃; for 0.0833333h; Microwave irradiation; in air;

DOI:10.1021/co100011g

Reference yield: 58.0%

→ C19H23BO3 (946409-21-8)

Guidance literature:

Reference yield:

bis(pinacol)diborane (73183-34-3) → C19H23BO3 (946409-21-8)

Guidance literature:

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; In 1,4-dioxane; at 120 ℃; for 12h; Inert atmosphere; Schlenk technique;

DOI:10.1002/anie.201807181

upstream raw materials:

4-bromomethylphenylboronic acid pinacol ester

phenol

bis(pinacol)diborane

Downstream raw materials:

C₂₀H₁₆O₂

Refernces

• 1、 Spencer, John,Baltus, Christine B.,Patel, Hiren,Press, Neil J.,Callear, Samantha K.,Male, Louise,Coles, Simon J.. "Microwave-mediated synthesis of an arylboronate library". experimental part. p. 24 - 31. Retrieved 2011/04/15.