N-Methyl-N-trimethylsilylmethyl-N'-tert-butylformamidine

Base Information

• Chemical Name: N-Methyl-N-trimethylsilylmethyl-N'-tert-butylformamidine
• CAS No.: 80376-66-5
• Molecular Formula: C10H24N2Si
• Molecular Weight: 200.4
• DSSTox Substance ID: DTXSID40369764
• Mol file: 80376-66-5.mol

Synonyms:80376-66-5;N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE;N'-tert-butyl-N-methyl-N-(trimethylsilylmethyl)methanimidamide;DTXSID40369764;AG-H-23116;FT-0695857;(E)-N'-tert-butyl-N-methyl-N-((trimethylsilyl)methyl)formimidamide

Chemical Property of N-Methyl-N-trimethylsilylmethyl-N'-tert-butylformamidine

Chemical Property:

• Refractive Index: 1.45-1.452
• Boiling Point: 78-80 °C (7 mmHg)
• PSA: 15.60000
• LogP: 3.04070
• Storage Temp.: 0-6°C
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 200.170875308
• Heavy Atom Count: 13
• Complexity: 174

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 20/21/22
• Safety Statements: 36/37

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)N=CN(C)C[Si](C)(C)C

Technology Process of N-Methyl-N-trimethylsilylmethyl-N'-tert-butylformamidine

There total 1 articles about N-Methyl-N-trimethylsilylmethyl-N'-tert-butylformamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.2%

chloro-trimethyl-silane (75-77-4) + (E)-N′-tert-butyl-N,N-dimethylformimidamide (119044-70-1) → N'-tert-Butyl-N-methyl-N-trimethylsilanylmethyl-formamidine (80376-66-5)

Guidance literature:

With sec.-butyllithium; In tetrahydrofuran; -78 deg C -> room temperature;

DOI:10.1021/ja00367a052

Reference yield:

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + N'-tert-Butyl-N-methyl-N-trimethylsilanylmethyl-formamidine (80376-66-5) → N'-tert-Butyl-N-cyclohexylidenemethyl-N-methyl-formamidine

Guidance literature:

With n-butyllithium; In tetrahydrofuran; -78 deg C -> 0 deg C;

DOI:10.1021/ja00367a052

Reference yield:

benzaldehyde (100-52-7) + N'-tert-Butyl-N-methyl-N-trimethylsilanylmethyl-formamidine (80376-66-5) → N'-tert-Butyl-N-methyl-N-((E)-styryl)-formamidine (80376-67-6)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; -78 deg C -> 0 deg C;

DOI:10.1021/ja00367a052

upstream raw materials:

chloro-trimethyl-silane

(E)-N′-tert-butyl-N,N-dimethylformimidamide

Downstream raw materials:

N'-tert-Butyl-N-methyl-N-((1E,3E)-4-phenyl-buta-1,3-dienyl)-formamidine

racem. 2,6-Dimethyl-1-cyan-cyclohexan

N'-tert-Butyl-N-(2,2-diphenyl-vinyl)-N-methyl-formamidine

cyclohex-2-enecarbonitrile