Adenine, 1-ethyl- (7CI,8CI)

Base Information

• Chemical Name: Adenine, 1-ethyl- (7CI,8CI)
• CAS No.: 21802-48-2
• Molecular Formula: C7H9 N5
• Molecular Weight: 163.182
• Hs Code.: 2933990090
• Mol file: 21802-48-2.mol

Synonyms:Adenine,1-ethyl- (7CI,8CI); 1-Ethyladenine

Chemical Property of Adenine, 1-ethyl- (7CI,8CI)

Chemical Property:

• Vapor Pressure: 0.0158mmHg at 25°C
• Boiling Point: 256°Cat760mmHg
• Flash Point: 108.6°C
• PSA: 69.62000
• Density: 1.49g/cm³
• LogP: 1.00960

Purity/Quality:

1-ethyl-1H-Purin-6-amine 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Adenine, 1-ethyl- (7CI,8CI)

There total 5 articles about Adenine, 1-ethyl- (7CI,8CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-ethyladenosine hydriodide (75018-23-4) → 1-ethyladenine (21802-48-2)

Guidance literature:

With hydrogenchloride; Amberlite IRA-402 (HCO₃^-); Yield given. Multistep reaction; 1) 92-94 dec C, 30 min;

DOI:10.1248/cpb.38.3463

Reference yield:

adenosine (58-61-7) → 1-ethyladenine (21802-48-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 54 percent / AcNMe₂ / 90 h / 35 - 38 °C

2: 1) 0.5 N HCl, 2) Amberlite IRA-402 (HCO₃^-) / 1) 92-94 dec C, 30 min

With hydrogenchloride; N,N-dimethyl acetamide; Amberlite IRA-402 (HCO₃^-);

DOI:10.1248/cpb.38.3463

Reference yield:

ethyl iodide (75-03-6) + adenosine (58-61-7) → 1-ethyladenine (21802-48-2)

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1248/cpb.38.3463

upstream raw materials:

1-ethyladenosine hydriodide

1-Ethyladenosine

ethyl iodide

adenosine

Downstream raw materials:

5-amino-N-ethylimidazole-4-carboxamide

1-ethylhypoxanthine

hypoxanthine

N₆-Ethyladenine

Refernces

• 1、 Lawley,Orr,Jarman. "Isolation and identification of products from alkylation of nucleic acids: ethyl- and isopropyl purines". . p. 73 - 84,77,78. Retrieved 2007/10/04.