2-(((tert-butyldiMethylsilyl)oxy)Methyl)-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine

Base Information

Chemical Name:2-(((tert-butyldiMethylsilyl)oxy)Methyl)-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine
CAS No.:1351378-73-8
Molecular Formula:C18H32BNO3Si
Molecular Weight:349.353
Hs Code.:
Mol file:1351378-73-8.mol

Synonyms:2-(((tert-butyldiMethylsilyl)oxy)Methyl)-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine;6-([(tert-Butyldimethylsilyl)oxy]methyl)pyridine-3-boronic acid pinacol ester

Suppliers and Price of 2-(((tert-butyldiMethylsilyl)oxy)Methyl)-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 4 raw suppliers

Chemical Property of 2-(((tert-butyldiMethylsilyl)oxy)Methyl)-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine

Chemical Property:

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-(((tert-butyldiMethylsilyl)oxy)Methyl)-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine

There total 1 articles about 2-(((tert-butyldiMethylsilyl)oxy)Methyl)-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-(((tert-butyldimethylsilyl)oxy)methyl)pyridine

: 73183-34-3
bis(pinacol)diborane

: 880495-84-1
2-(((tert-Butyldimethylsilyl)oxy)methyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

: 1351378-73-8
2-({[tert-butyl(dimethyl)silyl]oxy}methyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

Guidance literature:: bis(pinacol)diborane; With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 3-(2-(2-(dicyclohexylboraneyl)ethyl)phenyl)-1,10-phenanthroline; 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane; In 1,4-dioxane; at 25 ℃; for 0.166667h; Inert atmosphere; Glovebox;

2-(((tert-butyldimethylsilyl)oxy)methyl)pyridine; In hexane; at 25 ℃; for 18h; Overall yield = 62 %; Overall yield = 0.22 g; regioselective reaction; Inert atmosphere; Glovebox;
DOI:10.1021/jacs.9b03138

Reference yield: 95.0%

: 1351378-73-8
2-({[tert-butyl(dimethyl)silyl]oxy}methyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

: meso-tetrakis(2,6-dimethyl-4-triflyloxyphenyl)porphyrin

: meso-tetrakis[2,6-dimethyl-4-(6-tert-butyldimethylsilyloxymethylpyrid-3-yl)phenyl]porphyrin

Guidance literature:: With potassium phosphate; palladium diacetate; XPhos; In tetrahydrofuran; water; N,N-dimethyl-formamide; at 95 ℃; Inert atmosphere;
DOI:10.1016/j.tetlet.2011.11.045

Reference yield: 84.0%

: 1351378-73-8
2-({[tert-butyl(dimethyl)silyl]oxy}methyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

: 1416438-86-2
1-iodo-2,4,6-tris(trifluoromethyl)benzene

: 2-(((tert-butyldimethylsilyl)oxy)methyl)-5-(2,4,6-tris(trifluoromethyl)phenyl)pyridine

Guidance literature:: With potassium phosphate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In water; toluene; at 100 ℃; for 24h; Inert atmosphere;