[(Z)-2-(benzenesulfonyl)prop-1-enyl]benzene

Base Information

• Chemical Name: [(Z)-2-(benzenesulfonyl)prop-1-enyl]benzene
• CAS No.: 30246-74-3
• Molecular Formula: C15H14 O2 S
• Molecular Weight: 258.341
• NSC Number: 140179
• ChEMBL ID: CHEMBL490100
• Mol file: 30246-74-3.mol

Synonyms:NSC140179;CHEMBL490100;30246-74-3;NSC-140179

Chemical Property of [(Z)-2-(benzenesulfonyl)prop-1-enyl]benzene

Chemical Property:

• Vapor Pressure: 1.54E-07mmHg at 25°C
• Boiling Point: 440.3°Cat760mmHg
• Flash Point: 271°C
• Density: 1.193g/cm³
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 258.07145086
• Heavy Atom Count: 18
• Complexity: 377

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=CC1=CC=CC=C1)S(=O)(=O)C2=CC=CC=C2
• Isomeric SMILES: C/C(=C/C1=CC=CC=C1)/S(=O)(=O)C2=CC=CC=C2

Technology Process of [(Z)-2-(benzenesulfonyl)prop-1-enyl]benzene

There total 31 articles about [(Z)-2-(benzenesulfonyl)prop-1-enyl]benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

ethyl phenyl sulfone (599-70-2) + benzaldehyde (100-52-7) + diethyl chlorophosphate (814-49-3) → {[(1E)-1-phenylprop-1-en-2-yl]sulfonyl}benzene (30246-74-3)

Guidance literature:

ethyl phenyl sulfone; With n-butyllithium; In tetrahydrofuran; hexane; at 0 ℃; for 0.5h;

diethyl chlorophosphate; In tetrahydrofuran; at 0 ℃; for 0.5h;

benzaldehyde; at 0 ℃; for 1h;

DOI:10.1080/00397910008087319

Reference yield: 81.0%

1-phenylpropadiene (2327-99-3) + sodium benzenesulfonate (873-55-2) → {[(1E)-1-phenylprop-1-en-2-yl]sulfonyl}benzene (30246-74-3)

Guidance literature:

With eosin y; In N,N-dimethyl-formamide; at 25 ℃; for 5h; diastereoselective reaction; Inert atmosphere; Irradiation;

DOI:10.1021/acs.joc.9b02960

Reference yield: 73.0%

cis-1-phenyl-1-propylene (766-90-5) + benzenesulfonyl chloride (98-09-9) → 1-propenylbenzene (873-66-5) + {[(1E)-1-phenylprop-1-en-2-yl]sulfonyl}benzene (30246-74-3)

Guidance literature:

With dichlorotris(triphenylphosphine)ruthenium(II); triethylamine; In benzene; at 60 ℃; for 72h; Yields of byproduct given; sealed tube;

DOI:10.1246/bcsj.57.1421

upstream raw materials:

((1R,2R)-2-Benzenesulfonyl-1-phenyl-propyl)-dimethyl-amine

(E)-5-phenyl-4-phenylsulfonyl-4-penten-2-ol

1-propenylbenzene

benzenesulfonyl chloride

Downstream raw materials:

1-(benzenesulfonyl)-1-phenylpropan-2-one

(E)-((1-phenylprop-1-en-2-yl)sulfonyl)benzene

1-propenylbenzene