(3aS,4R,6aR)-4-Methoxytetrahydrofuro[3,4-b]furan-2(3H)-one

Base Information

Chemical Name:(3aS,4R,6aR)-4-Methoxytetrahydrofuro[3,4-b]furan-2(3H)-one
CAS No.:866594-61-8
Molecular Formula:C₇H₁₀O₄
Molecular Weight:158.154
Hs Code.:
DSSTox Substance ID:DTXSID301188395
Mol file:866594-61-8.mol

Synonyms:866594-61-8;(3aS,4R,6aR)-4-Methoxytetrahydrofuro[3,4-b]furan-2(3H)-one;(3aS,4R,6aR)-4-methoxy-3a,4,6,6a-tetrahydro-3H-furo[2,3-c]furan-2-one;(3aS,4R,6aR)-Tetrahydro-4-methoxyfuro[3,4-b]furan-2(3H)-one;starbld0001103;SCHEMBL8077875;DTXSID301188395;(3aS,4R,6aR)-4-methoxy-hexahydrofuro[3,4-b]furan-2-one

Suppliers and Price of (3aS,4R,6aR)-4-Methoxytetrahydrofuro[3,4-b]furan-2(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(3aS,4R,6aR)-Tetrahydro-4-methoxyfuro[3,4-b]furan-2(3H)-one
25mg
$ 1320.00

Medical Isotopes, Inc.
(3aS,4R,6aR)-Tetrahydro-4-methoxyfuro[3,4-β]furan-2(3H)-one
100 mg
$ 2280.00

Medical Isotopes, Inc.
(3aS,4R,6aR)-Tetrahydro-4-methoxyfuro[3,4-β]furan-2(3H)-one
10 mg
$ 660.00

American Custom Chemicals Corporation
(3AS,4R,6AR)-TETRAHYDRO-4-METHOXYFURO[3,4-B]FURAN-2(3H)-ONE 95.00%
5MG
$ 496.50

Total 5 raw suppliers

Chemical Property of (3aS,4R,6aR)-4-Methoxytetrahydrofuro[3,4-b]furan-2(3H)-one

Chemical Property:

Boiling Point:311.6±42.0 °C(Predicted)
PSA：44.76000
Density:1.26±0.1 g/cm3(Predicted)
LogP:-0.07920
XLogP3:-0.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:158.05790880
Heavy Atom Count:11
Complexity:179

Purity/Quality:

95%+ or 98%+ ^*data from raw suppliers

(3aS,4R,6aR)-Tetrahydro-4-methoxyfuro[3,4-b]furan-2(3H)-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1C2CC(=O)OC2CO1
Isomeric SMILES:CO[C@H]1[C@H]2CC(=O)O[C@H]2CO1
Uses An impurity in the preparation of Bisfuranol.

Technology Process of (3aS,4R,6aR)-4-Methoxytetrahydrofuro[3,4-b]furan-2(3H)-one

There total 3 articles about (3aS,4R,6aR)-4-Methoxytetrahydrofuro[3,4-b]furan-2(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 501921-23-9
(R)-3-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-4-nitro-butyric acid ethyl ester

: 124-41-4
sodium methylate

: 866594-61-8
(3aS,4R,6aR)-4-methoxy-tetrahydro-furo[3.4-b]furan-2(3H)-one

: 866594-60-7
(3aS,4S,6aR)-4-methoxy-tetrahydro-furo[3.4-b]furan-2(3H)-one

: ((2S,3R,4R)-4-Hydroxy-2-methoxy-tetrahydro-furan-3-yl)-acetic acid methyl ester

Guidance literature:: (R)-3-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-4-nitro-butyric acid ethyl ester; sodium methylate; With methanol; at 0 - 5 ℃; for 3h;

With sulfuric acid; In methanol; at 0 - 5 ℃;
DOI:10.1021/ol052554i

Reference yield:

: 67-56-1
methanol

: C₁₁H₁₉NO₆

: 866594-61-8
(3aS,4R,6aR)-4-methoxy-tetrahydro-furo[3.4-b]furan-2(3H)-one

: 866594-60-7
(3aS,4S,6aR)-4-methoxy-tetrahydro-furo[3.4-b]furan-2(3H)-one

Guidance literature:: With sulfuric acid; at 0 ℃; for 4.67h; Product distribution / selectivity;

Reference yield:

: 917877-01-1
R-3-(2,2-dimethyl[1,3]dioxolan-4-yl)-acrylic acid ethyl ester

: 67-56-1
methanol

: 75-52-5
nitromethane

: 866594-61-8
(3aS,4R,6aR)-4-methoxy-tetrahydro-furo[3.4-b]furan-2(3H)-one

: 866594-60-7
(3aS,4S,6aR)-4-methoxy-tetrahydro-furo[3.4-b]furan-2(3H)-one

Guidance literature:: R-3-(2,2-dimethyl[1,3]dioxolan-4-yl)-acrylic acid ethyl ester; methanol; nitromethane; With sodium methylate; at 0 ℃; for 18h;

With sulfuric acid; at -30 - 0 ℃; for 21.25h; Product distribution / selectivity;