1-[(4R)-4-(phenylMethyl)-2-thioxo-3-oxazolidinyl]-1-Propanone

Base Information

Chemical Name:1-[(4R)-4-(phenylMethyl)-2-thioxo-3-oxazolidinyl]-1-Propanone
CAS No.:334968-78-4
Molecular Formula:C₁₃H₁₅NO₂S
Molecular Weight:249.334
Hs Code.:
Mol file:334968-78-4.mol

Synonyms:1-[(4R)-4-(phenylMethyl)-2-thioxo-3-oxazolidinyl]-1-Propanone

Suppliers and Price of 1-[(4R)-4-(phenylMethyl)-2-thioxo-3-oxazolidinyl]-1-Propanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 1-[(4R)-4-(phenylMethyl)-2-thioxo-3-oxazolidinyl]-1-Propanone

Chemical Property:

PSA：61.63000
LogP:2.08930

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 1-[(4R)-4-(phenylMethyl)-2-thioxo-3-oxazolidinyl]-1-Propanone

There total 5 articles about 1-[(4R)-4-(phenylMethyl)-2-thioxo-3-oxazolidinyl]-1-Propanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 802294-64-0,79-09-4
propionic acid

: (R)-4-benzyl-2-oxazolidinethione

: 334968-78-4
(R)-1-(4-benzyl-2-thioxooxazolidin-3-yl)propan-1-one

Guidance literature:: With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 4h; Cooling with ice;
DOI:10.1002/anie.201201395

Reference yield: 90.0%

: 79-03-8
propionyl chloride

: 131744-19-9,145588-94-9
(4S)-4-benzyl-1,3-oxazolidine-2-thione

: 145588-95-0,334968-78-4
N-propanoyl-(S)-4-benzyl-1,3-oxazolidine-2-thione

Guidance literature:: (4S)-4-benzyl-1,3-oxazolidine-2-thione; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.333333h;

propionyl chloride; In tetrahydrofuran; hexane; at -78 - 20 ℃;
DOI:10.1021/jo001387r