methyl 2-(methylsulfonyl)-7-phenylthieno[3,2-d]pyrimidine-6-carboxylate

Base Information

Chemical Name:methyl 2-(methylsulfonyl)-7-phenylthieno[3,2-d]pyrimidine-6-carboxylate
CAS No.:1462949-87-6
Molecular Formula:C₁₅H₁₂N₂O₄S₂
Molecular Weight:348.403
Hs Code.:
Mol file:1462949-87-6.mol

Synonyms:methyl 2-(methylsulfonyl)-7-phenylthieno[3,2-d]pyrimidine-6-carboxylate

Suppliers and Price of methyl 2-(methylsulfonyl)-7-phenylthieno[3,2-d]pyrimidine-6-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of methyl 2-(methylsulfonyl)-7-phenylthieno[3,2-d]pyrimidine-6-carboxylate

Chemical Property:

Purity/Quality:: 98%min ^*data from raw suppliers

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Technology Process of methyl 2-(methylsulfonyl)-7-phenylthieno[3,2-d]pyrimidine-6-carboxylate

There total 6 articles about methyl 2-(methylsulfonyl)-7-phenylthieno[3,2-d]pyrimidine-6-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1462949-88-7
methyl 2-(methylsulfanyl)-7-phenylthieno[3,2-d]pyrimidine-6-carboxylate

: 1462949-87-6
methyl 2-(methylsulfonyl)-7-phenylthieno[3,2-d]pyrimidine-6-carboxylate

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 20 ℃; Cooling with ice;

Reference yield:

: 1462949-86-5
methyl 2-(methylsulfonyl)-7-{[(trifluoromethyl)sulfonyl]oxy}thieno[3,2-d]pyrimidine-6-carboxylate

: 98-80-6
phenylboronic acid

: 1462949-87-6
methyl 2-(methylsulfonyl)-7-phenylthieno[3,2-d]pyrimidine-6-carboxylate

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate; In toluene; at 90 ℃; for 0.5h;

Reference yield:

: 61727-33-1
5-chloro-2-(methylthio)pyrimidine-4-carboxylic acid

: 1462949-87-6
methyl 2-(methylsulfonyl)-7-phenylthieno[3,2-d]pyrimidine-6-carboxylate

Guidance literature:: Multi-step reaction with 5 steps

1: chloro-trimethyl-silane / dichloromethane / 20 h / 20 °C

2: sodium hydride / N,N-dimethyl-formamide; mineral oil / 3.25 h / 20 - 60 °C

3: pyridine / 48 h / 20 °C

4: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; tert-butylimino-tri(pyrrolidino)phosphorane / 1,4-dioxane / 20 h / Inert atmosphere; Reflux

5: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 20 °C / Cooling with ice

With pyridine; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; chloro-trimethyl-silane; sodium hydride; 3-chloro-benzenecarboperoxoic acid; tert-butylimino-tri(pyrrolidino)phosphorane; In 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide; mineral oil;