Methyl 5-chloro-2-(methylthio)pyrimidine-4-carboxylate

Base Information

Chemical Name:Methyl 5-chloro-2-(methylthio)pyrimidine-4-carboxylate
CAS No.:79686-03-6
Molecular Formula:C7H7ClN2O2S
Molecular Weight:218.664
Hs Code.:2933599090
DSSTox Substance ID:DTXSID60406100
Wikidata:Q82210982
Mol file:79686-03-6.mol

Synonyms:79686-03-6;Methyl 5-chloro-2-(methylthio)pyrimidine-4-carboxylate;methyl 5-chloro-2-methylsulfanylpyrimidine-4-carboxylate;5-Chloro-2-(methylthio)-4-pyrimidinecarboxylic Acid Methyl Ester;5-Chloro-2-methylsulfanyl-pyrimidine-4-carboxylic acid methyl ester;methyl5-chloro-2-(methylthio)pyrimidine-4-carboxylate;4-Pyrimidinecarboxylic acid, 5-chloro-2-(methylthio)-, methyl ester;methyl 5-chloro-2-(methylsulfanyl)pyrimidine-4-carboxylate;methyl 5-chloro-2-methylthiopyrimidine-4-carboxylate;SCHEMBL4225491;AMY4868;DTXSID60406100;MFCD06496440;STK614648;AKOS000267891;SB58085;AS-47540;CS-0148292;FT-0690201;F14201;AS-871/43307674;Methyl 5-chloro-2-(methylthio)-pyrimidine-4-carboxylate;methyl 5-chloro-2-(methylsulfanyl)-4-pyrimidinecarboxylate;Methyl 5-Chloro-2-(methylthio)pyrimidine-4-carboxylate, AldrichCPR

Suppliers and Price of Methyl 5-chloro-2-(methylthio)pyrimidine-4-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Chloro-2-(methylthio)-4-pyrimidinecarboxylicAcidMethylEster
25g
$ 1075.00

TRC
5-Chloro-2-(methylthio)-4-pyrimidinecarboxylicAcidMethylEster
10g
$ 525.00

Crysdot
Methyl5-chloro-2-(methylthio)pyrimidine-4-carboxylate 95+%
10g
$ 454.00

Atlantic Research Chemicals
Methyl5-Chloro-2-(methylthio)pyrimidine-4-carboxylate 95%
1gm:
$ 116.64

American Custom Chemicals Corporation
METHYL-5-CHLORO-2-(METHYLTHIO)PYRIMIDINE-4-CARBOXYLATE 95.00%
5MG
$ 496.27

Alichem
Methyl5-chloro-2-(methylthio)pyrimidine-4-carboxylate
10g
$ 494.64

AK Scientific
Methyl5-chloro-2-(methylthio)pyrimidine-4-carboxylate
1g
$ 151.00

Total 8 raw suppliers

Chemical Property of Methyl 5-chloro-2-(methylthio)pyrimidine-4-carboxylate

Chemical Property:

PSA：77.38000
LogP:1.63850
XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:217.9916763
Heavy Atom Count:13
Complexity:193

Purity/Quality:

97% ^*data from raw suppliers

5-Chloro-2-(methylthio)-4-pyrimidinecarboxylicAcidMethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1=NC(=NC=C1Cl)SC
Uses 5-Chloro-2-(methylthio)-4-pyrimidinecarboxylic Acid Methyl Ester is a synthetic intermediate in the preparation of GSK3β inhibitors and non-nucleoside reverse transcriptase inhibitors for treating H IV infection. 5-Chloro-2-(methylthio)-4-pyrimidinecarboxylic Acid Methyl Ester is a synthetic intermediate in the preparation of GSK3β inhibitors and non-nucleoside reverse transcriptase inhibitors for treating HIV infection.

Technology Process of Methyl 5-chloro-2-(methylthio)pyrimidine-4-carboxylate

There total 3 articles about Methyl 5-chloro-2-(methylthio)pyrimidine-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 67-56-1
methanol

: 61727-33-1
5-chloro-2-(methylthio)pyrimidine-4-carboxylic acid

: 79686-03-6
methyl 5-chloro-2-(methylsulfanyl)pyrimidine-4-carboxylate

Guidance literature:: 5-chloro-2-(methylthio)pyrimidine-4-carboxylic acid; With oxalyl dichloride; In dichloromethane; N,N-dimethyl-formamide; at 0 - 15 ℃; for 2h;

methanol; In dichloromethane; N,N-dimethyl-formamide; at 0 - 15 ℃; for 2h;