2H-2-Ethyl Candesartan Cilexetil

Base Information

Chemical Name:2H-2-Ethyl Candesartan Cilexetil
CAS No.:914613-36-8
Molecular Formula:C35H38N6O6
Molecular Weight:638.71282
Hs Code.:
Mol file:914613-36-8.mol

Synonyms:2H-2-Ethyl Candesartan Cilexetil;2-Ethoxy-1-[[2'-(2-ethyl-2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- 1H-Benzimidazole-7-carboxylic acid 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester;Candesartan Cilexetil N2-Ethyl IMpurity;Candesartan Cilexetil EP Impurity F

Suppliers and Price of 2H-2-Ethyl Candesartan Cilexetil

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2H-2-EthylCandesartanCilexetil
250mg
$ 1455.00

Total 12 raw suppliers

Chemical Property of 2H-2-Ethyl Candesartan Cilexetil

Chemical Property:

Melting Point:97-99°C
PSA：132.48000
Density:1.32
LogP:6.81240
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

99%, ^*data from raw suppliers

2H-2-EthylCandesartanCilexetil ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 2H-2-Ethyl Candesartan Cilexetil (Candesartan Cilexetil EP Impurity F) is a Candesartan Cilexetil impurity. Candesartan Cilexetil impurity.

Technology Process of 2H-2-Ethyl Candesartan Cilexetil

There total 3 articles about 2H-2-Ethyl Candesartan Cilexetil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

candesartan cilexetil: 145040-37-5
candesartan cilexetil

: 869631-11-8
(1RS)-1-[[(cyclohexyloxy)carbonyl]oxy]ethyl 2-oxo-3-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-2,3-dihydro-1H-benzimidazole-4-carboxylate

: 914613-36-8
(1RS)-1-[[(cyclohexyloxy)carbonyl]oxy]ethyl 2-ethoxy-1-[[2'-(2-ethyl-2H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylate

Guidance literature:: In ethanol; at 50 ℃; for 31h; Product distribution / selectivity;

Reference yield:

: 75-03-6
ethyl iodide

candesartan cilexetil: 145040-37-5
candesartan cilexetil

: 914613-35-7
(1RS)-1-[[(cyclohexyloxy)carbonyl]oxy]ethyl 2-ethoxy-1-[[2'-(1-ethyl-1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylate

: 914613-36-8
(1RS)-1-[[(cyclohexyloxy)carbonyl]oxy]ethyl 2-ethoxy-1-[[2'-(2-ethyl-2H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylate

Guidance literature:: candesartan cilexetil; With potassium carbonate; In acetone; at 20 ℃; for 1h; Inert atmosphere;

ethyl iodide; In acetone; at 20 ℃; for 24h;
DOI:10.1135/cccc2008072