2-Allylindane

Base Information

• Chemical Name: 2-Allylindane
• CAS No.: 24329-97-3
• Molecular Formula: C₁₂H₁₄
• Molecular Weight: 158.243
• Hs Code.: 2902909090
• DSSTox Substance ID: DTXSID70702867
• Nikkaji Number: J114.393J
• Wikidata: Q82634885
• Mol file: 24329-97-3.mol

Synonyms:24329-97-3;2-Allylindane;Indan, 2-allyl-;DTXSID70702867;2-(Prop-2-en-1-yl)-2,3-dihydro-1H-indene

Chemical Property of 2-Allylindane

Chemical Property:

• PSA: 0.00000
• LogP: 2.97750
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 2
• Exact Mass: 158.109550447
• Heavy Atom Count: 12
• Complexity: 145

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=CCC1CC2=CC=CC=C2C1

Technology Process of 2-Allylindane

There total 7 articles about 2-Allylindane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

indan-2-yl p-toluenesulphonate (17783-69-6) + allyl alcohol (107-18-6) → 2-allyl-2,3-dihydro-1H-indene (24329-97-3)

Guidance literature:

allyl alcohol; With 1,1,1,3,3,3-hexamethyl-disilazane; at 25 ℃; for 8h; Inert atmosphere;

indan-2-yl p-toluenesulphonate; With vinylmagnesium chloride; nickel dichloride; In tetrahydrofuran; diethyl ether; at 25 ℃; for 16h; Inert atmosphere; Glovebox;

DOI:10.1021/acs.orglett.1c02616

Reference yield:

indan-2-ol (4254-29-9) → 2-allyl-2,3-dihydro-1H-indene (24329-97-3)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) MeSO₂Cl, Py, (ii) NaI, acetone

2: (i) Mg, Et₂O, (ii) /BRN= 605308/

DOI:10.1139/v69-745

Reference yield:

1-indene (95-13-6) → 2-allyl-2,3-dihydro-1H-indene (24329-97-3)

Guidance literature:

Multi-step reaction with 4 steps

1: ethanol / Irradiation

2: HCl / diethyl ether

3: LiAlH₄ / diethyl ether / Heating

4: (i) MeSO₂Cl, Py, (ii) NaI, acetone

With hydrogenchloride; lithium aluminium tetrahydride; In diethyl ether; ethanol;

DOI:10.1139/v69-745

upstream raw materials:

2-iodoindane

allyl bromide

indan-2-ol

1-indene

Refernces