Levothyroxine Related Compound (N-Acetyl 3,5-diiodo-L-tyrosine Methyl Ester)

Base Information

• Chemical Name: Levothyroxine Related Compound (N-Acetyl 3,5-diiodo-L-tyrosine Methyl Ester)
• CAS No.: 56460-41-4
• Molecular Formula: C₁₂H₁₃I₂NO₄
• Molecular Weight: 489.049

Synonyms:Levothyroxine Related Compound (N-Acetyl 3,5-diiodo-L-tyrosine Methyl Ester)

Chemical Property of Levothyroxine Related Compound (N-Acetyl 3,5-diiodo-L-tyrosine Methyl Ester)

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

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Technology Process of Levothyroxine Related Compound (N-Acetyl 3,5-diiodo-L-tyrosine Methyl Ester)

There total 3 articles about Levothyroxine Related Compound (N-Acetyl 3,5-diiodo-L-tyrosine Methyl Ester) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) → 3.5-diiodo-N-acetyl-L-tyrosine methyl ester (56460-41-4)

Guidance literature:

With hydrogenchloride;

DOI:10.1021/ja01348a034

Reference yield:

3,5-diiodo-L-thyrosine methyl ester (76318-50-8) + acetic anhydride (108-24-7) → 3.5-diiodo-N-acetyl-L-tyrosine methyl ester (56460-41-4)

Guidance literature:

DOI:10.1021/ja01348a034

Reference yield:

3,5-diiodo-L-thyrosine methyl ester (76318-50-8) + acetyl chloride (75-36-5) → 3.5-diiodo-N-acetyl-L-tyrosine methyl ester (56460-41-4)

Guidance literature:

DOI:10.1021/ja01348a034

upstream raw materials:

3,5-diiodo-L-thyrosine methyl ester

acetic anhydride

acetyl chloride

methanol

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