4-FLUORO-3-IODO-6-INDAZOLECARBOXYLIC ACID METHYL ESTER

Base Information

Chemical Name:4-FLUORO-3-IODO-6-INDAZOLECARBOXYLIC ACID METHYL ESTER
CAS No.:885521-35-7
Molecular Formula:C9H6FIN2O2
Molecular Weight:320.062
Hs Code.:
Mol file:885521-35-7.mol

Synonyms:4-FLUORO-3-IODO-6-INDAZOLECARBOXYLIC ACID METHYL ESTER;Methyl 4-fluoro-3-iodo-1H-indazole-6-carboxylate;4-Fluoro-3-iodoindazole-6-carboxylic acid methyl ester

Suppliers and Price of 4-FLUORO-3-IODO-6-INDAZOLECARBOXYLIC ACID METHYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Methyl4-fluoro-3-iodo-1H-indazole-6-carboxylate 95+%
5g
$ 1173.00

Crysdot
Methyl4-fluoro-3-iodo-1H-indazole-6-carboxylate 95+%
1g
$ 465.00

Chemenu
methyl4-fluoro-3-iodo-1H-indazole-6-carboxylate 95%
1g
$ 439.00

Chemenu
methyl4-fluoro-3-iodo-1H-indazole-6-carboxylate 95%
5g
$ 1105.00

American Custom Chemicals Corporation
4-FLUORO-3-IODO-6-INDAZOLECARBOXYLIC ACID METHYL ESTER 95.00%
5MG
$ 505.58

Alichem
Methyl4-fluoro-3-iodo-1H-indazole-6-carboxylate
5g
$ 1658.25

Alichem
Methyl4-fluoro-3-iodo-1H-indazole-6-carboxylate
1g
$ 730.30

Total 8 raw suppliers

Chemical Property of 4-FLUORO-3-IODO-6-INDAZOLECARBOXYLIC ACID METHYL ESTER

Chemical Property:

PSA：54.98000
LogP:2.09320

Purity/Quality:

97% ^*data from raw suppliers

Methyl4-fluoro-3-iodo-1H-indazole-6-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-FLUORO-3-IODO-6-INDAZOLECARBOXYLIC ACID METHYL ESTER

There total 4 articles about 4-FLUORO-3-IODO-6-INDAZOLECARBOXYLIC ACID METHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 885521-44-8
methyl 4-fluoro-1H-indazole-6-carboxylate

: 885521-35-7
methyl 4-fluoro-3-iodo-1H-indazole-6-carboxylate

Guidance literature:: With iodine; potassium hydroxide; In N,N-dimethyl-formamide; at 20 ℃; for 4h;

Reference yield:

: 123843-67-4
4-bromo-2,6-difluorobenzonitrile

: 885521-35-7
methyl 4-fluoro-3-iodo-1H-indazole-6-carboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: hydrazine hydrate / ethanol / 2 h / 90 °C / Inert atmosphere

2: hypophosphorous acid; isopentyl nitrite / ethanol / 0 - 20 °C

3: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; triethylamine / 16 h / 70 °C / 2585.81 Torr

4: iodine; potassium hydroxide / N,N-dimethyl-formamide / 4 h / 20 °C

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; iodine; hypophosphorous acid; hydrazine hydrate; triethylamine; potassium hydroxide; isopentyl nitrite; In ethanol; N,N-dimethyl-formamide;

Reference yield:

: 1227912-19-7
6-bromo-4-fluoro-1H-indazol-3-amine

: 885521-35-7
methyl 4-fluoro-3-iodo-1H-indazole-6-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: hypophosphorous acid; isopentyl nitrite / ethanol / 0 - 20 °C

2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; triethylamine / 16 h / 70 °C / 2585.81 Torr

3: iodine; potassium hydroxide / N,N-dimethyl-formamide / 4 h / 20 °C

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; iodine; hypophosphorous acid; triethylamine; potassium hydroxide; isopentyl nitrite; In ethanol; N,N-dimethyl-formamide;