1H-Benz[de]isoquinoline-1,3(2H)-dione, 2-(2-aminoethyl)-6-(dimethylamino)-

Base Information

Chemical Name:1H-Benz[de]isoquinoline-1,3(2H)-dione, 2-(2-aminoethyl)-6-(dimethylamino)-
CAS No.:1051373-06-8
Molecular Formula:C16H17N3O2
Molecular Weight:283.33
Hs Code.:
Mol file:1051373-06-8.mol

Synonyms:1H-Benz[de]isoquinoline-1,3(2H)-dione, 2-(2-aminoethyl)-6-(dimethylamino)-

Suppliers and Price of 1H-Benz[de]isoquinoline-1,3(2H)-dione, 2-(2-aminoethyl)-6-(dimethylamino)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1H-Benz[de]isoquinoline-1,3(2H)-dione, 2-(2-aminoethyl)-6-(dimethylamino)-

Chemical Property:

Melting Point:153.3-155.3 °C
Boiling Point:479.4±35.0 °C(Predicted)
PSA：68.33000
Density:1.312±0.06 g/cm3(Predicted)
LogP:1.67770

Purity/Quality:: NLT 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1H-Benz[de]isoquinoline-1,3(2H)-dione, 2-(2-aminoethyl)-6-(dimethylamino)-

There total 9 articles about 1H-Benz[de]isoquinoline-1,3(2H)-dione, 2-(2-aminoethyl)-6-(dimethylamino)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1051373-04-6
tert-butyl (2-(6-(dimethylamino)-1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)ethyl)carbamate

: 1051373-06-8
2-(2-aminoethyl)-6-(N,N-dimethylamino)-1H-benzo[de]isoquinoline-1,3(2H)-dione

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 4h;
DOI:10.1021/ml300475m

Reference yield: 85.0%

: 77976-79-5
4-(N,N-dimethylamino)-1,8-naphthalic anhydride

: 107-15-3,85404-18-8
ethylenediamine

: 1051373-06-8
2-(2-aminoethyl)-6-(N,N-dimethylamino)-1H-benzo[de]isoquinoline-1,3(2H)-dione

Guidance literature:: In ethanol; for 1.5h; Inert atmosphere; Reflux;
DOI:10.1007/s00706-010-0337-x

Reference yield:

: 57260-73-8
N-BOC-1,2-diaminoethane

: 77976-79-5
4-(N,N-dimethylamino)-1,8-naphthalic anhydride

: 1051373-06-8
2-(2-aminoethyl)-6-(N,N-dimethylamino)-1H-benzo[de]isoquinoline-1,3(2H)-dione

Guidance literature:: N-BOC-1,2-diaminoethane; 4-(N,N-dimethylamino)-1,8-naphthalic anhydride; With triethylamine; In isopropyl alcohol; at 80 ℃; for 12h; Inert atmosphere;

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 3h;