4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-ol

Base Information

Chemical Name:4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-ol
CAS No.:1429757-65-2
Molecular Formula:C15H10Cl2FN3O2
Molecular Weight:354.168
Hs Code.:
Mol file:1429757-65-2.mol

Synonyms:4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-ol

Suppliers and Price of 4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Acrotein
4-((3,4-Dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-ol 97%
0.25g
$ 400.00

Total 17 raw suppliers

Chemical Property of 4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-ol

Chemical Property:

Boiling Point:475.2±45.0 °C(Predicted)
PKA:8.08±0.40(Predicted)
PSA：67.27000
Density:1.563±0.06 g/cm3(Predicted)
LogP:4.60650

Purity/Quality:

99%, ^*data from raw suppliers

4-((3,4-Dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-ol 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-ol

There total 4 articles about 4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.38%

: 1429757-64-1
4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate

: 1429757-65-2
4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-ol

Guidance literature:: With ammonium hydroxide; In methanol; at 10 - 20 ℃; for 3h;

Reference yield: 78.0%

: 574745-97-4
4-chloro-6-hydroxy-7-methoxyquinazoline

: 886762-39-6
3,4-dichloro-2-fluorobenzeneamine

: 1429757-65-2
4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-ol

Guidance literature:: With water; In water; isopropyl alcohol; for 6h; Reflux;

Reference yield:

: 230955-75-6
6-acetoxy-4-chloro-7-methoxyquinazoline

: 1429757-65-2
4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-ol

Guidance literature:: Multi-step reaction with 2 steps

1: toluene

2: ammonium hydroxide / methanol / 80 °C

With ammonium hydroxide; In methanol; toluene;