4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate

Base Information

Chemical Name:4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate
CAS No.:1429757-64-1
Molecular Formula:C₁₇H₁₂Cl₂FN₃O₃
Molecular Weight:396.205
Hs Code.:

Synonyms:4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate

Suppliers and Price of 4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 8 raw suppliers

Chemical Property of 4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate

Chemical Property:

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of 4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate

There total 3 articles about 4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 886762-39-6
3,4-dichloro-2-fluorobenzeneamine

: 179688-53-0
6-acetoxy-7-methoxy-3,4-dihydroquinazolin-4-one

: 1429757-64-1
4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate

Guidance literature:: 6-acetoxy-7-methoxy-3,4-dihydroquinazolin-4-one; With N-ethyl-N,N-diisopropylamine; trichlorophosphate; In toluene; at 75 ℃; for 3.33333h;

3,4-dichloro-2-fluorobenzeneamine; In toluene; for 2h; Heating;

Reference yield: 80.4%

: 886762-39-6
3,4-dichloro-2-fluorobenzeneamine

: 230955-75-6
6-acetoxy-4-chloro-7-methoxyquinazoline

: 1429757-64-1
4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate

Guidance literature:: In toluene; for 2h;

Reference yield:

: 179688-53-0
6-acetoxy-7-methoxy-3,4-dihydroquinazolin-4-one

: 1429757-64-1
4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine; trichlorophosphate / toluene / 80 °C

2: toluene

With triethylamine; trichlorophosphate; In toluene;