S-(+)-2-Octanol

Base Information

• Chemical Name: S-(+)-2-Octanol
• CAS No.: 113301-48-7
• Molecular Formula: C8H18O
• Molecular Weight: 130.22792
• Mol file: 113301-48-7.mol

Synonyms:2-Octanol, (2S)-; 2-Octanol, (S)-; d-Octan-2-ol; D(+)-2-Octanol; (S)-octan-2-ol; (S)-2-Octanol

Chemical Property of S-(+)-2-Octanol

Chemical Property:

• Boiling Point: 175℃
• Flash Point: 71℃
• Density: 0.822
• Water Solubility.: 1 g/L (20℃)

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Hazard Codes: Xi:Irritant
• Statements: R36/37/38:
• Safety Statements: S26:; S36:

MSDS Files:

Useful:

Technology Process of S-(+)-2-Octanol

There total 593 articles about S-(+)-2-Octanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

methanol (67-56-1) + Octanal (124-13-0) + hexyl-methyl-ketone (111-13-7) → 1,1-dimethoxyoctane (10022-28-3) + rac-octan-2-ol (4128-31-8,113301-48-7,4128-32-9)

Guidance literature:

methanol; Octanal; hexyl-methyl-ketone; With Ru_nanoHAP; at 30 ℃; for 0.5h; Flow reactor; Inert atmosphere;

With hydrogen; at 40 ℃; for 1h; under 760.051 Torr; Flow reactor;

DOI:10.1039/c3gc41322e

Reference yield: 98.0%

2-octyl tert-butyldimethylsilyl ether (53060-25-6,114127-43-4,92976-54-0) → rac-octan-2-ol (4128-31-8,113301-48-7,4128-32-9)

Guidance literature:

With polymer-supported dicyanoketene acetal; water; In acetonitrile; at 20 ℃; for 10h;

DOI:10.1055/s-2001-16073

Reference yield:

2-iodooctane (36049-78-2,557-36-8) → rac-octan-2-ol (4128-31-8,113301-48-7,4128-32-9) + trans-2-Octene (13389-42-9) + oct-1-ene (111-66-0,25068-25-1)

Guidance literature:

With sodium hydroxide; In ethanol; at 30 ℃; for 24h; Product distribution; other fluorinated iodoalkanes; also with NaOMe;

DOI:10.1021/jo00187a012

upstream raw materials:

methyl magnesium iodide

heptanal

n-Octylamine

ethanol

Downstream raw materials:

2-chlorocarbonyloxy-octane

trimethyl-(1-methyl-heptyloxy)-silane

diphenyl-dithiophosphinic acid-(1-methyl-heptyl ester)

N,N'-bis-(4-dimethylamino-phenyl)-terephthalamide