1-O,2-O,3-O,5-O-Tetrakis(trimethylsilyl)-D-ribofuranose

Base Information

• Chemical Name: 1-O,2-O,3-O,5-O-Tetrakis(trimethylsilyl)-D-ribofuranose
• CAS No.: 56271-69-3
• Molecular Formula: C₁₇H₄₂O₅Si₄
• Molecular Weight: 438.859
• Mol file: 56271-69-3.mol

Synonyms:1-O,2-O,3-O,5-O-Tetrakis(trimethylsilyl)-D-ribofuranose

Chemical Property of 1-O,2-O,3-O,5-O-Tetrakis(trimethylsilyl)-D-ribofuranose

Chemical Property:

• PSA: 46.15000
• LogP: 4.85450

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-O,2-O,3-O,5-O-Tetrakis(trimethylsilyl)-D-ribofuranose

There total 2 articles about 1-O,2-O,3-O,5-O-Tetrakis(trimethylsilyl)-D-ribofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

trimethylsilyl acetate (2754-27-0) + D-Ribose (532-20-7,613-83-2,7261-25-8,7687-39-0,13221-22-2,14795-83-6,15761-67-8,20074-49-1,25545-03-3,25545-04-4,32445-75-3,34436-17-4,36441-93-7,36468-53-8,37110-85-3,37388-49-1,38029-69-5,40461-77-6,40461-89-0,41546-19-4,41546-20-7,41546-21-8,41546-26-3,41546-29-6,41546-30-9,41546-31-0,126872-16-0,131064-98-7) → D-(-)-ribofuranose, tetrakis(trimethylsilyl) ether (56271-69-3)

Guidance literature:

With triethylamine; In neat (no solvent); at 25 ℃; for 8h; Inert atmosphere;

DOI:10.1055/s-0040-1705990

Reference yield:

chloro-trimethyl-silane (75-77-4) + sorangiadenosine + 1,1,1,3,3,3-hexamethyl-disilazane (999-97-3) → D-(-)-ribofuranose, tetrakis(trimethylsilyl) ether (56271-69-3)

Guidance literature:

sorangiadenosine; With potassium hydroxide; In methanol; at 20 ℃; for 2h;

With hydrogenchloride; In methanol; at 65 ℃; for 15h;

chloro-trimethyl-silane; 1,1,1,3,3,3-hexamethyl-disilazane; With pyridine; at 20 ℃; for 0.5h;

DOI:10.1021/ol800061h

upstream raw materials:

chloro-trimethyl-silane

1,1,1,3,3,3-hexamethyl-disilazane

trimethylsilyl acetate

D-Ribose

Refernces

• 1、 Ahn, Jong-Woong,Jang, Kyoung Hwa,Chung, Soon-Chun,Oh, Ki-Bong,Shin, Jongheon. "Sorangiadenosine, a new sesquiterpene adenoside from the myxobacterium Sorangium cellulosum". body text. p. 1167 - 1169. Retrieved 2009/04/06.