4H-Thiopyran-4-one,5-bis(p-methoxybenzylidene)-, 1,1-dioxide

Base Information

Chemical Name:4H-Thiopyran-4-one,5-bis(p-methoxybenzylidene)-, 1,1-dioxide
CAS No.:61448-81-5
Molecular Formula:C21H20O5S
Molecular Weight:384.4455
Hs Code.:
NSC Number:144302
ChEMBL ID:CHEMBL3410527

Synonyms:MLS002920620;NSC144302;CHEMBL3410527;4H-Thiopyran-4-one,5-bis(p-methoxybenzylidene)-, 1,1-dioxide;NSC-144302;61448-81-5

Suppliers and Price of 4H-Thiopyran-4-one,5-bis(p-methoxybenzylidene)-, 1,1-dioxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4H-Thiopyran-4-one,5-bis(p-methoxybenzylidene)-, 1,1-dioxide

Chemical Property:

Vapor Pressure:2.41E-18mmHg at 25°C
Boiling Point:679.9°Cat760mmHg
Flash Point:365°C
Density:1.311g/cm³
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:384.10314491
Heavy Atom Count:27
Complexity:633

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C=C2CS(=O)(=O)CC(=CC3=CC=C(C=C3)OC)C2=O
Isomeric SMILES:COC1=CC=C(C=C1)/C=C\2/C(=O)/C(=C/C3=CC=C(C=C3)OC)/CS(=O)(=O)C2

Technology Process of 4H-Thiopyran-4-one,5-bis(p-methoxybenzylidene)-, 1,1-dioxide

There total 7 articles about 4H-Thiopyran-4-one,5-bis(p-methoxybenzylidene)-, 1,1-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 61448-77-9
tetrahydro-3,5-bis-[(4-methoxyphenyl)methylene]-4H-thiopyran-4-one

: 61448-81-5
(3Z,5Z)-3,5-bis[(4-methoxyphenyl)methylene]tetrahydro-4H-thiopyran-4-one 1,1-dioxide

Guidance literature:: With dihydrogen peroxide; acetic acid; In ethanol; for 0.5h; Heating;
DOI:10.1021/jm00354a018

Reference yield: 50.0%

: 123-11-5
4-methoxy-benzaldehyde

: 17396-35-9
1,1-dioxotetrahydrothiopyran-4-one

: 61448-81-5
(3Z,5Z)-3,5-bis[(4-methoxyphenyl)methylene]tetrahydro-4H-thiopyran-4-one 1,1-dioxide

Guidance literature:: With hydrogenchloride; In ethanol; water; Reflux;
DOI:10.1021/jm501336h

Reference yield:

: 1072-72-6
Tetrahydrothiopyran-4-one

: 61448-81-5
(3Z,5Z)-3,5-bis[(4-methoxyphenyl)methylene]tetrahydro-4H-thiopyran-4-one 1,1-dioxide

Guidance literature:: Multi-step reaction with 2 steps

1: 66 percent / conc. HCl / ethanol / Heating

2: 60 percent / 30percent H₂O₂, glacial acetic acid / ethanol / 0.5 h / Heating

With hydrogenchloride; dihydrogen peroxide; acetic acid; In ethanol;
DOI:10.1021/jm00354a018