1-(4-Methoxybenzyl)-4-nitro-1H-imidazole-5-carboxylic acid

Base Information

Chemical Name:1-(4-Methoxybenzyl)-4-nitro-1H-imidazole-5-carboxylic acid
CAS No.:1450627-92-5
Molecular Formula:C₁₂H₁₁N₃O₅
Molecular Weight:277.236
Hs Code.:
Mol file:1450627-92-5.mol

Synonyms:1-(4-Methoxybenzyl)-4-nitro-1H-imidazole-5-carboxylic acid

Suppliers and Price of 1-(4-Methoxybenzyl)-4-nitro-1H-imidazole-5-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of 1-(4-Methoxybenzyl)-4-nitro-1H-imidazole-5-carboxylic acid

Chemical Property:

Purity/Quality:: 95+% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-(4-Methoxybenzyl)-4-nitro-1H-imidazole-5-carboxylic acid

There total 1 articles about 1-(4-Methoxybenzyl)-4-nitro-1H-imidazole-5-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 1450627-82-3
1-(4-methoxybenzyl)-4-nitro-5-styryl-1H-imidazole

: 1450627-92-5
1-(4-methoxybenzyl)-4-nitro-1H-imidazole-5-carboxylic acid

: 65-85-0,8013-63-6
benzoic acid

Guidance literature:: With potassium permanganate; sodium hydroxide; In water; at 0 - 5 ℃;
DOI:10.1016/j.bmc.2013.06.069

Reference yield: 87.0%

: 1450627-92-5
1-(4-methoxybenzyl)-4-nitro-1H-imidazole-5-carboxylic acid

: 22483-09-6
2,2-dimethoxyethylamine

: 1450627-93-6
1-(4-methoxybenzyl)-N-(2,2-dimethoxyethyl)-4-nitro-1H-imidazole-5-carboxamide

Guidance literature:: 1-(4-methoxybenzyl)-4-nitro-1H-imidazole-5-carboxylic acid; 2,2-dimethoxyethylamine; With 1,1'-carbonyldiimidazole; In tetrahydrofuran; Reflux; Inert atmosphere;

2,2-dimethoxyethylamine; In tetrahydrofuran; at 20 ℃; for 2h;
DOI:10.1016/j.bmc.2013.06.069

Reference yield:

: 1450627-92-5
1-(4-methoxybenzyl)-4-nitro-1H-imidazole-5-carboxylic acid

: 1450627-73-2
5-methoxy-1-(4-methoxybenzyl)-4,5,6,7-tetrahydro-imidazo[4,5-e][1,4]diazepin-8(1H)-one

Guidance literature:: Multi-step reaction with 4 steps

1.1: 1,1'-carbonyldiimidazole / tetrahydrofuran / Reflux; Inert atmosphere

1.2: 2 h / 20 °C

2.1: palladium on activated charcoal; hydrogen / methanol / 5 h / 2068.65 Torr

3.1: hydrogenchloride; water / 20 °C

4.1: hydrogenchloride / water / 5 h / 20 °C

With hydrogenchloride; palladium on activated charcoal; water; hydrogen; 1,1'-carbonyldiimidazole; In tetrahydrofuran; methanol; water;
DOI:10.1016/j.bmc.2013.06.069