(2-Chloro-thiazol-5-ylMethyl)-Methyl-aMine

Base Information

• Chemical Name: (2-Chloro-thiazol-5-ylMethyl)-Methyl-aMine
• CAS No.: 120740-06-9
• Molecular Formula: C5H7ClN2S
• Molecular Weight: 162.643
• Hs Code.: 2934100090
• Mol file: 120740-06-9.mol

Synonyms:(2-Chloro-thiazol-5-ylMethyl)-Methyl-aMine;1-(2-Chlorothiazol-5-yl)-N-methylmethanamine;5-Thiazolemethanamine, 2-chloro-N-methyl-;1-(2-chloro-1,3-thiazol-5-yl)-N-methylmethanamine

Chemical Property of (2-Chloro-thiazol-5-ylMethyl)-Methyl-aMine

Chemical Property:

• PSA: 53.16000
• LogP: 1.90680

Purity/Quality:

97% ^*data from raw suppliers

1-(2-Chlorothiazol-5-yl)-N-methylmethanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2-Chloro-thiazol-5-ylMethyl)-Methyl-aMine

There total 2 articles about (2-Chloro-thiazol-5-ylMethyl)-Methyl-aMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

α-Cl-β-thiazolyl chloride (105827-91-6) + methylamine (74-89-5) → N-(2-chloro-5-thiazolylmethyl)-N-methylamine (120740-06-9)

Guidance literature:

In ethanol; water; at 0 - 20 ℃; for 5h;

Reference yield:

magnesium sulfate (7487-88-9) + α-Cl-β-thiazolyl chloride (105827-91-6) → N-(2-chloro-5-thiazolylmethyl)-N-methylamine (120740-06-9)

Guidance literature:

With sodium hydroxide; methylamine; In ethanol; dichloromethane;

Reference yield: 73.0%

N-(2-chloro-5-thiazolylmethyl)-N-methylamine (120740-06-9) + 2-methyl-4-(5-(trifluoromethyl)-5-(3,4,5-trifluorophenyl)-4,5-dihydroisoxazol-3-yl)benzoic acid → N-((2-chlorothiazol-5-yl)methyl)-4-(5-(3,4,5-trifluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-2-methyl-N-methylbenzamide

Guidance literature:

2-methyl-4-(5-(trifluoromethyl)-5-(3,4,5-trifluorophenyl)-4,5-dihydroisoxazol-3-yl)benzoic acid; With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; for 1h;

N-(2-chloro-5-thiazolylmethyl)-N-methylamine; With triethylamine; In dichloromethane;

upstream raw materials:

magnesium sulfate

α-Cl-β-thiazolyl chloride

methylamine