Technology Process of 4-(2,6-DICHLOROPHENYL)-1-BUTENE
There total 3 articles about 4-(2,6-DICHLOROPHENYL)-1-BUTENE which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Allyl acetate;
With
bis(η3-allyl-μ-chloropalladium(II)); Tri(p-tolyl)phosphine;
In
tetrahydrofuran;
for 0.5h;
Schlenk technique;
Sealed tube;
Inert atmosphere;
2,6-dichlorobenzaldehyde hydrazone;
With
lithium tert-butoxide;
In
tetrahydrofuran;
at 45 ℃;
for 24h;
chemoselective reaction;
Schlenk technique;
Sealed tube;
Inert atmosphere;
DOI:10.1002/anie.201809112
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: hydrazine hydrate / tetrahydrofuran / 50 °C / Sealed tube; Inert atmosphere
2.1: bis(η3-allyl-μ-chloropalladium(II)); Tri(p-tolyl)phosphine / tetrahydrofuran / 0.5 h / Schlenk technique; Sealed tube; Inert atmosphere
2.2: 24 h / 45 °C / Schlenk technique; Sealed tube; Inert atmosphere
With
bis(η3-allyl-μ-chloropalladium(II)); hydrazine hydrate; Tri(p-tolyl)phosphine;
In
tetrahydrofuran;
DOI:10.1002/anie.201809112
- Guidance literature:
-
With
lithium chloride;
Yield given. Multistep reaction;
1.) THF, from -70 to -20 deg C, 5 min, 2.) a) THF, from -70 to 0 deg C, 3 h, b) 0 deg C, 5 min;
DOI:10.1021/jo00259a038
