1,2,O-Isopropylidene-6-O-methylsulfonyl-a-D-glucofuranose

Base Information

• Chemical Name: 1,2,O-Isopropylidene-6-O-methylsulfonyl-a-D-glucofuranose
• CAS No.: 33557-25-4
• Molecular Formula: C₁₀H₁₈O₈S
• Molecular Weight: 298.314
• Hs Code.: 29400090
• Mol file: 33557-25-4.mol

Synonyms:1,2,O-Isopropylidene-6-O-methylsulfonyl-a-D-glucofuranose;1,2,O-Isopropylidene-6-O-methylsulfonyl-α-D-glucofuranose

Chemical Property of 1,2,O-Isopropylidene-6-O-methylsulfonyl-a-D-glucofuranose

Chemical Property:

• PSA: 119.90000
• LogP: -0.35840

Purity/Quality:

98%Min ^*data from raw suppliers

1,2,O-Isopropylidene-6-O-methylsulfonyl-a-D-glucofuranose ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 1,2-O-Isopropylidene-6-methyl-sulfonyl-α-D-glucofuranose (cas# 33557-25-4) is a compound useful in organic synthesis.

Technology Process of 1,2,O-Isopropylidene-6-O-methylsulfonyl-a-D-glucofuranose

There total 6 articles about 1,2,O-Isopropylidene-6-O-methylsulfonyl-a-D-glucofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanesulfonyl chloride (124-63-0) + 1,2-O-isopropylidene-α-D-glucofuranose (18549-40-1) → 1,2-O-isopropylidene-α-D-glucofuranos-6-yl methanesulfonate (33557-25-4)

Guidance literature:

With pyridine; chloroform; at -15 ℃;

Reference yield:

1,2:5,6-di-O-isopropylidene-α-D-glucofuranose (582-52-5) → 1,2-O-isopropylidene-α-D-glucofuranos-6-yl methanesulfonate (33557-25-4)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride / water

2: pyridine

With pyridine; hydrogenchloride; In water;

DOI:10.1134/S1070428014050091

Reference yield:

D-Glucose (2280-44-6) → 1,2-O-isopropylidene-α-D-glucofuranos-6-yl methanesulfonate (33557-25-4)

Guidance literature:

Multi-step reaction with 3 steps

1: copper(II) sulfate; sulfuric acid

2: hydrogenchloride / water

3: pyridine

With pyridine; hydrogenchloride; sulfuric acid; copper(II) sulfate; In water;

DOI:10.1134/S1070428014050091

upstream raw materials:

methanesulfonyl chloride

1,2-O-isopropylidene-α-D-glucofuranose

D-glucose

1,2:5,6-di-O-isopropylidene-α-D-glucofuranose

Downstream raw materials:

3,5-di-O-acetyl-6-deoxy-1,2-O-isopropylidene-6-azido-α-D-glucofuranose

3,5-O-benzylidene-6-deoxy-1,2-O-isopropylidene-6-methylsulfonyloxy-α-D-glucofuranose

6-amino-6-deoxy-1,2-O-isopropylidene-α-D-glucofuranose

6-deoxy-6-[(1S,2S,5R)-2-isopropyl-5-methylcyclohexylsulfanyl]-1,2-O-isopropylidene-α-D-glucofuranose