2-(Triphenylphosphoranylidene)hydrazonoacetic acid ethyl ester

Base Information

• Chemical Name: 2-(Triphenylphosphoranylidene)hydrazonoacetic acid ethyl ester
• CAS No.: 22610-15-7
• Molecular Formula: C22H21N2O2P
• Molecular Weight: 376.395
• Mol file: 22610-15-7.mol

Synonyms:2-(Triphenylphosphoranylidene)hydrazonoacetic acid ethyl ester;α-Ethoxy-α-oxoacetaldehyde (triphenylphosphoranylidene)hydrazone

Chemical Property of 2-(Triphenylphosphoranylidene)hydrazonoacetic acid ethyl ester

Chemical Property:

• PSA: 60.83000
• LogP: 3.71300

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(Triphenylphosphoranylidene)hydrazonoacetic acid ethyl ester

There total 3 articles about 2-(Triphenylphosphoranylidene)hydrazonoacetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

diazoacetic acid ethyl ester (623-73-4) + triphenylphosphine (603-35-0) → (triphenylphosphoranylidene-hydrazono)-acetic acid ethyl ester (22610-15-7)

Guidance literature:

In dichloromethane; pentane; at 20 ℃; for 4h; Inert atmosphere; Glovebox;

DOI:10.1039/c8dt02420k

Reference yield:

diazoacetic acid ethyl ester (623-73-4) + ethanol (64-17-5) + carbon monoxide (201230-82-2) + triphenylphosphine (603-35-0) → (triphenylphosphoranylidene-hydrazono)-acetic acid ethyl ester (22610-15-7) + diethyl malonate (105-53-3)

Guidance literature:

With Co₂(CO)5(CHCO₂Et)(PPh₃)2; In dichloromethane; at 10 ℃; under 750.075 Torr;

DOI:10.1021/om100480v

Reference yield:

→ (triphenylphosphoranylidene-hydrazono)-acetic acid ethyl ester (22610-15-7)

Guidance literature:

upstream raw materials:

diazoacetic acid ethyl ester

triphenylphosphine

ethanol

carbon monoxide

Downstream raw materials:

triphenylphosphine sulfide

{[5-(4-Methoxy-phenyl)-3-oxo-3H-furan-(2E)-ylidene]-hydrazono}-acetic acid ethyl ester

{[3-Oxo-5-p-tolyl-3H-furan-(2E)-ylidene]-hydrazono}-acetic acid ethyl ester

{[5-(4-Bromo-phenyl)-3-oxo-3H-furan-(2E)-ylidene]-hydrazono}-acetic acid ethyl ester

Refernces

• 1、 Ungvari, Neszta,Foerdos, Eszter,Balogh, Janos,Kegl, Tamas,Parkanyi, Laszlo,Ungvary, Ferenc. "Triphenylphosphane-modified cobalt catalysts for the selective carbonylation of ethyl diazoacetate". experimental part. p. 3837 - 3851. Retrieved 2010/12/24.