4-Benzylbenzeneboronic acid pinacol ester, 97%

Base Information

• Chemical Name: 4-Benzylbenzeneboronic acid pinacol ester, 97%
• CAS No.: 911708-01-5
• Molecular Formula: C₁₉H₂₃BO₂
• Molecular Weight: 294.201
• Hs Code.: 2931900090
• Mol file: 911708-01-5.mol

Synonyms:4-Benzylbenzeneboronic acid pinacol ester, 97%;2-(4-Benzylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;4-Benzylphenylboronic acid pinacol ester

Chemical Property of 4-Benzylbenzeneboronic acid pinacol ester, 97%

Chemical Property:

• Melting Point: 90-93°C
• PSA: 18.46000
• LogP: 3.57660
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

4-Benzylphenylboronic acid pinacol ester ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 4-Benzylphenylboronic acid pinacol ester

Technology Process of 4-Benzylbenzeneboronic acid pinacol ester, 97%

There total 13 articles about 4-Benzylbenzeneboronic acid pinacol ester, 97% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

1-methyl-4-(phenylmethyl)benzene (620-83-7) + bis(pinacol)diborane (73183-34-3) → 2-(4-benzylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (911708-01-5)

Guidance literature:

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; In 1,2-dimethoxyethane; dimethyl sulfoxide; at 80 ℃; Inert atmosphere;

Reference yield: 87.0%

2-(4-iodophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (73852-88-7) + benzyl alcohol (100-51-6,185532-71-2) → 2-(4-benzylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (911708-01-5)

Guidance literature:

2-(4-iodophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; benzyl alcohol; With cobalt(II) phthalocyanine; N-ethyl-N,N-diisopropylamine; zinc; Methanesulfonic anhydride; In N,N-dimethyl acetamide; at 20 ℃; for 1h;

With nickel(II) bromide trihydrate; at 20 ℃;

DOI:10.1039/c4sc03106g

Reference yield: 85.0%

4-fluorodiphenylmethane (587-79-1) + bis(pinacol)diborane (73183-34-3) → 2-(4-benzylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (911708-01-5)

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; lithium hexamethyldisilazane; In toluene; at 80 ℃; for 12h; Inert atmosphere; Schlenk technique;

DOI:10.1021/acs.orglett.8b02228

upstream raw materials:

C₁₅H₁₉BCl₃NO₃

benzene

(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol

1-benzyl-4-bromo-benzene

Downstream raw materials:

(R)-4-(4-benzylphenyl)-4-methyl-1,2,3-oxathiazolidine 2,2-dioxide

Refernces

• 1、 K?nig, Burkhard,Wang, Hua,Wang, Shun. "Photo-induced thiolate catalytic activation of inert Caryl-hetero bonds for radical borylation". supporting information. p. 1653 - 1665. Retrieved 2021/06/17.
• 2、 Chen, Xiao-Yue,Huang, Yu-Hao,Zhou, Jian,Wang, Peng. "Pd-Catalyzed Site-Selective Borylation of Simple Arenes via Thianthrenation?". supporting information. p. 1269 - 1272. Retrieved 2020/08/13.