587-79-1

Basic information

• Product Name: 4-FLUORODIPHENYLMETHANE
• Synonyms: 4-FluorodiphenylmethaneDISC 05/09/02 see # 9194;1-Benzyl-4-fluorobenzene;4-FLUORODIPHENYLMETHANE;4-Fluorodiphenylmethane 99%;4-Fluorodiphenylmethane99%
• CAS NO: 587-79-1
• Molecular Formula: C₁₃H₁₁F
• Molecular Weight: 186.22
• Mol File: 587-79-1.mol
• Article Data: 85

Chemical Properties

• Boiling Point: 94°C 1mm
• Appearance: /
• Density: 1
• Refractive Index: 1.5540 to 1.5580
• CAS DataBase Reference: 4-FLUORODIPHENYLMETHANE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-FLUORODIPHENYLMETHANE(587-79-1)
• EPA Substance Registry System: 4-FLUORODIPHENYLMETHANE(587-79-1)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 587-79-1(Hazardous Substances Data)

Usage

General Description

4-Fluorodiphenylmethane is a chemical compound with the molecular formula C13H11F. It is a white crystalline powder that is insoluble in water but soluble in organic solvents. 4-FLUORODIPHENYLMETHANE is used in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. It is also used as a building block in organic chemistry to create a variety of different compounds. While it has potential uses in various industries, 4-fluorodiphenylmethane should be handled with care and in accordance with proper safety precautions due to its potential health hazards if mishandled.

Upstream product

• 352-11-4 1-chloromethyl-4-fluorobenzene 
• 71-43-2 benzene 
• 462-06-6 fluorobenzene 
• 100-44-7 benzyl chloride 
• 108-86-1 bromobenzene 
• 3831-29-6 4-fluorobenzyl iodide 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 459-57-4 4-fluorobenzaldehyde 
• 185246-53-1 2-(4-fluorophenyl)-1,3-dioxane 
• 101-81-5 Diphenylmethane 
• 64-19-7 acetic acid 
• 98-80-6 phenylboronic acid 
• 617-86-7 triethylsilane 
• 451-40-1 phenyl benzyl ketone 

Downstream Products

• 911708-01-5 2-(4-benzylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 101-81-5 Diphenylmethane 
• 365-21-9 1-(chlorophenylmethyl)-4-fluorobenzene 
• 620-86-0 4-Benzylbenzoic acid 
• 912588-50-2 N-((4-fluorophenyl)(phenyl)methyl)-4-methylbenzenesulfonamide 
• 437-23-0 ((4-fluorophenyl)methylene)dibenzene 
• 39768-73-5 {4-[(4-Fluoro-phenyl)-phenyl-methyl]-phenyl}-dimethyl-amine 
• 39768-74-6 C₂₀H₁₇FO 
• 39768-79-1 C₂₀H₁₄F₄ 
• 386-95-8 bis-(4-fluoro-phenyl)-phenyl-methane 
• 1443984-93-7 2-((4-fluorophenyl)(phenyl)methyl)pyridine 
• 1443985-00-9 C₂₀H₁₄FN 

Relevant articles and documents

Nickel-Catalyzed Electrochemical C(sp3)?C(sp2) Cross-Coupling Reactions of Benzyl Trifluoroborate and Organic Halides**

Reported here is the redox neutral electrochemical C(sp2)?C(sp3) cross-coupling reaction of bench-stable aryl halides or β-bromostyrene (electrophiles) and benzylic trifluoroborates (nucleophiles) using nonprecious, bench-stable NiCl2?glyme/polypyridine catalysts in an undivided cell configuration under ambient conditions. The broad reaction scope and good yields of the Ni-catalyzed electrochemical coupling reactions were confirmed by 50 examples of aryl/β-styrenyl chloride/bromide and benzylic trifluoroborates. Potential applications were demonstrated by electrosynthesis and late-stage functionalization of pharmaceuticals and natural amino acid modification, and three reactions were run on gram-scale in a flow-cell electrolyzer. The electrochemical C?C cross-coupling reactions proceed through an unconventional radical transmetalation mechanism. This method is highly productive and expected to find wide-spread applications in organic synthesis.

Alumina grafted SBA-15 sustainable bifunctional catalysts for direct cross-coupling of benzylic alcohols to diarylmethanes

AlSBA-15 catalysts possessing Br?nsted acid and Lewis acid-base bifunctionalities catalyze the direct arylation of benzyl alcohols to diarylmethanes with an 85% product yield through C-O bond activation. 2 and 4wt%AlSBA-15 catalysts have been synthesised by adopting a simple and efficient post-synthetic metal implantation route. The synthesised catalysts were characterized using XRD, N2 adsorption and desorption, 27Al MAS NMR, XPS, HR-TEM, NH3 and CO2-temperature-programmed desorption (TPD) and pyridine-transmission-FTIR spectroscopy techniques to confirm the existence of Br?nsted acid and Lewis acid-base bifunctionalities. Through various control experiments, it is verified that Br?nsted acid sites activate the benzyl alcohol and Lewis base sites interact with phenylboronic acid concurrently to accomplish the coupling reaction. In the recyclability study, 4wt%AlSBA-15 preserves its activity and stability up to 5 cycles. The 4wt%AlSBA-15 catalyst unlike homogeneous catalysts does not require additives, long reaction time and expensive metals.

Super electron donor-mediated reductive desulfurization reactions

The desulfurization of thioacetals and thioethers by a pyridine-derived electron donor is described. This methodology provides efficient access to the reduced products in high yields and does not require the use of transition-metals, elemental alkali-metals, or hydrogen atom donors.