5-(4-fluorophenyl)-1H-imidazol-2-amine

Base Information

Chemical Name:5-(4-fluorophenyl)-1H-imidazol-2-amine
CAS No.:60472-17-5
Molecular Formula:C9H8FN3
Molecular Weight:177.18
Hs Code.:2933290090
European Community (EC) Number:804-141-6
ChEMBL ID:CHEMBL1649771
DSSTox Substance ID:DTXSID00515124
Nikkaji Number:J2.573.327D
Wikidata:Q82375864
Mol file:60472-17-5.mol

Synonyms:5-(4-fluorophenyl)-1H-imidazol-2-amine;60472-17-5;2-Amino-5-(4-fluorophenyl)imidazole;SCHEMBL2419681;SCHEMBL8221175;CHEMBL1649771;DTXSID00515124;MFCD07382513;AKOS005638759;AKOS013153975;4-(4-fluorophenyl)-1H-imidazol-2-amine;BS-38290;CS-0246478;EN300-331446;5-(4-Fluorophenyl)-1H-imidazol-2-amine, AldrichCPR;F1907-0646;Z1198173214

Suppliers and Price of 5-(4-fluorophenyl)-1H-imidazol-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-(4-fluorophenyl)-1H-imidazol-2-amine
50mg
$ 45.00

Sigma-Aldrich
5-(4-Fluorophenyl)-1H-imidazol-2-amine Aldrich
1g
$ 388.00

ChemBridge Corporation
5-(4-fluorophenyl)-1H-imidazol-2-amine 95%
10 g
$ 980.00

American Custom Chemicals Corporation
5-(4-FLUOROPHENYL)-1H-IMIDAZOL-2-AMINE 95.00%
10G
$ 1994.98

American Custom Chemicals Corporation
5-(4-FLUOROPHENYL)-1H-IMIDAZOL-2-AMINE 95.00%
5G
$ 1334.03

American Custom Chemicals Corporation
5-(4-FLUOROPHENYL)-1H-IMIDAZOL-2-AMINE 95.00%
1G
$ 764.03

Total 9 raw suppliers

Chemical Property of 5-(4-fluorophenyl)-1H-imidazol-2-amine

Chemical Property:

Vapor Pressure:4.25E-07mmHg at 25°C
Boiling Point:415°C at 760 mmHg
Flash Point:204.8°C
PSA：54.70000
Density:1.334g/cm³
LogP:2.37920
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:177.07022543
Heavy Atom Count:13
Complexity:168

Purity/Quality:

97% ^*data from raw suppliers

5-(4-fluorophenyl)-1H-imidazol-2-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22-41
Safety Statements: 26-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=CN=C(N2)N)F

Technology Process of 5-(4-fluorophenyl)-1H-imidazol-2-amine

There total 5 articles about 5-(4-fluorophenyl)-1H-imidazol-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 397-53-5
2-(p-fluorophenyl)imidazo[1,2-a]pyrimidine

: 60472-17-5
4-(4-fluorophenyl)-1H-imidazol-2-ylamine

Guidance literature:: With hydrazine hydrate; In ethanol; at 120 ℃; for 0.166667h; Inert atmosphere; Microwave irradiation;
DOI:10.1016/j.tetlet.2009.06.128

Reference yield:

: 397-53-5
2-(p-fluorophenyl)imidazo[1,2-a]pyrimidine

: 60472-17-5
4-(4-fluoro-phenyl)-1⁽³⁾H-imidazol-2-ylamine

Guidance literature:: With hydrazine; In acetonitrile; at 120 ℃; for 0.416667h; Microwave irradiation;
DOI:10.1021/jm1011148

Reference yield:

: 403-29-2
2-bromo-4'-fluoroacetophenone

: 60472-17-5
4-(4-fluoro-phenyl)-1⁽³⁾H-imidazol-2-ylamine

Guidance literature:: Multi-step reaction with 2 steps

1: acetonitrile / 80 °C / Microwave irradiation

2: hydrazine / acetonitrile / 0.42 h / 120 °C / Microwave irradiation

With hydrazine; In acetonitrile;
DOI:10.1021/jm1011148