tert-butyl 4-(3-hydroxy-4-(methoxycarbonyl)phenoxy)piperidine-1-carboxylate

Base Information

• Chemical Name: tert-butyl 4-(3-hydroxy-4-(methoxycarbonyl)phenoxy)piperidine-1-carboxylate
• CAS No.: 162045-36-5
• Molecular Formula: C₁₈H₂₅NO₆
• Molecular Weight: 351.4
• Mol file: 162045-36-5.mol

Synonyms:tert-butyl 4-(3-hydroxy-4-(methoxycarbonyl)phenoxy)piperidine-1-carboxylate

Chemical Property of tert-butyl 4-(3-hydroxy-4-(methoxycarbonyl)phenoxy)piperidine-1-carboxylate

Chemical Property:

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl 4-(3-hydroxy-4-(methoxycarbonyl)phenoxy)piperidine-1-carboxylate

There total 3 articles about tert-butyl 4-(3-hydroxy-4-(methoxycarbonyl)phenoxy)piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

methyl 2,4-dihydroxybenzoate (2150-47-2) + t-butyl 4-hydroxy piperidine-1-carboxylate (109384-19-2) → 4-(N-t-Butoxycarbonyl-4-piperidinyloxy)-2-hydroxybenzoic acid methyl ester (162045-36-5)

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran;

DOI:10.1021/jm00023a002

Reference yield: 51.0%

N-(t-butoxy)-4-hydroxypiperidine + ethyl acetate n-hexane + methyl 2,4-dihydroxybenzoate (2150-47-2) + diethylazodicarboxylate (1972-28-7,218603-74-8) → 4-(N-t-Butoxycarbonyl-4-piperidinyloxy)-2-hydroxybenzoic acid methyl ester (162045-36-5)

Guidance literature:

With triphenylphosphine; In tetrahydrofuran; ethyl acetate;

Reference yield:

methyl 2,4-dihydroxybenzoate (2150-47-2) + t-butyl 4-hydroxy piperidine-1-carboxylate (109384-19-2) + diethylazodicarboxylate (1972-28-7,218603-74-8) → 4-(N-t-Butoxycarbonyl-4-piperidinyloxy)-2-hydroxybenzoic acid methyl ester (162045-36-5)

Guidance literature:

With triphenylphosphine; In tetrahydrofuran; hexane;

upstream raw materials:

methyl 2,4-dihydroxybenzoate

t-butyl 4-hydroxy piperidine-1-carboxylate

diethylazodicarboxylate

Downstream raw materials:

4-(N-t-Butoxycarbonyl-4-piperidinyloxy)-2-methoxybenzoic acid methyl ester

4-(N-t-Butoxycarbonyl-4-piperidinyloxy)-2-methoxy-benzoic acid

4-{3-Methoxy-4-[4-(2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-piperidine-1-carbonyl]-phenoxy}-piperidine-1-carboxylic acid tert-butyl ester

1-(1-{2-methoxy-4-[1-(2-methylpyridin-3-ylcarbonyl)piperidin-4-yloxy]benzoyl}piperidin-4-yl)-1,4-dihydrobenz[d][1,3]oxazin-2-one

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 162045-36-5 tert-butyl 4-(3-hydroxy-4-(methoxycarbonyl)phenoxy)piperidine-1-carboxylate

Send

Send

Metric Ton KG G Pound L ML

Send

Send